INT82214

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Context Info
Confidence 0.54
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.33
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (PTH) extracellular region (PTH) cell-cell signaling (PTH)
Anatomy Link Frequency
parathyroid 2
plasma 1
PTH (Homo sapiens)
Pain Link Frequency Relevance Heat
transdermal 7 100.00 Very High Very High Very High
Inflammation 18 99.16 Very High Very High Very High
chemokine 3 98.56 Very High Very High Very High
cytokine 72 93.40 High High
Inflammatory response 3 60.88 Quite High
fibrosis 6 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 21 99.16 Very High Very High Very High
Bone Cancer 20 96.12 Very High Very High Very High
Hypercalcemia 54 87.72 High High
Chronic Hepatitis 69 83.04 Quite High
Cirrhosis 30 81.56 Quite High
Hepatitis B Virus Infection 27 75.84 Quite High
Liver Disease 33 74.88 Quite High
Hepatitis 30 74.20 Quite High
Osteoporosis 123 73.60 Quite High
Pain 1 72.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One other interesting observation was that the mean plasma concentrations of PTH (1–34) with transdermal delivery peaked after about 5–10 min, whereas the peak was nearly 30 min after the subcutaneous injection, and the serum half-life after the transdermal administration was shorter (?
Transcription (peaked) of PTH in plasma associated with transdermal
1) Confidence 0.54 Published 2010 Journal Curr Osteoporos Rep Section Body Doc Link PMC2841260 Disease Relevance 0.08 Pain Relevance 0.14
After treatment had been started with vitamin D (calcitriol 2 x 0.25 micrograms/d) and calcium (calcium gluconate, 3 x 500 mg/d), the levels of calcium, PTH and enzymes in bone metabolism gradually became normal.
Transcription (levels) of PTH
2) Confidence 0.53 Published 1999 Journal Dtsch. Med. Wochenschr. Section Body Doc Link 10356581 Disease Relevance 0.21 Pain Relevance 0
Additional research is needed to determine when best to prescribe PTH in patients chronically treated with a bisphosphonate.
Transcription (prescribe) of PTH
3) Confidence 0.36 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC193734 Disease Relevance 0.14 Pain Relevance 0
IL-8 is a chemokine of importance in inflammatory processes, and causes an increase in the levels of parathyroid hormone (PTH) mRNA.
Transcription (levels) of parathyroid hormone in parathyroid associated with chemokine and inflammation
4) Confidence 0.18 Published 2005 Journal BMC Gastroenterol Section Body Doc Link PMC1242225 Disease Relevance 0.79 Pain Relevance 0.41
This could also explain the reduced effectivity of PTH in the presence of the immune interferon.
Transcription (effectivity) of PTH
5) Confidence 0.18 Published 2005 Journal BMC Gastroenterol Section Body Doc Link PMC1242225 Disease Relevance 1.31 Pain Relevance 0.15
IL-8 is a chemokine of importance in inflammatory processes, and causes an increase in the levels of parathyroid hormone (PTH) mRNA.
Transcription (levels) of PTH in parathyroid associated with chemokine and inflammation
6) Confidence 0.18 Published 2005 Journal BMC Gastroenterol Section Body Doc Link PMC1242225 Disease Relevance 0.80 Pain Relevance 0.41

General Comments

This test has worked.

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