INT82306

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Context Info
Confidence 0.68
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) extracellular region (Bdnf) nucleolus (Fos)
nucleus (Fos) cytoplasmic membrane-bounded vesicle (Bdnf) DNA binding (Fos)
Anatomy Link Frequency
spinal cord 2
Bdnf (Rattus norvegicus)
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 4 100.00 Very High Very High Very High
central sensitization 5 99.92 Very High Very High Very High
Dorsal horn neuron 1 99.84 Very High Very High Very High
nMDA receptor 1 98.00 Very High Very High Very High
Lasting pain 1 91.92 High High
hyperexcitability 1 87.60 High High
Inflammation 2 82.40 Quite High
antagonist 1 67.92 Quite High
IPN 2 64.72 Quite High
nociceptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 4 100.00 Very High Very High Very High
Pain 1 91.92 High High
Injury 1 90.08 High High
INFLAMMATION 2 82.40 Quite High
Inflammatory Pain 2 64.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BDNF, localized in primary sensory neuron cell bodies and central terminals, potentiates nociceptive spinal reflex responses in an in vitro spinal cord preparation and induces c-fos expression in dorsal horn neurons.
BDNF Positive_regulation (induces) of Gene_expression (expression) of c-fos in spinal cord associated with nociception, dorsal horn neuron and spinal cord
1) Confidence 0.68 Published 1999 Journal J. Neurosci. Section Abstract Doc Link 10366647 Disease Relevance 0.64 Pain Relevance 0.65

General Comments

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