INT82347

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Context Info
Confidence 0.60
First Reported 1999
Last Reported 2009
Negated 0
Speculated 3
Reported most in Abstract
Documents 5
Total Number 8
Disease Relevance 4.59
Pain Relevance 2.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PLXNA3) plasma membrane (PLXNA3) intracellular (PLXNA3)
Anatomy Link Frequency
plasma 1
fat 1
autonomic 1
ovary 1
PLXNA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 6 99.60 Very High Very High Very High
Dismenorea 4 99.10 Very High Very High Very High
Cluster headache 20 98.74 Very High Very High Very High
depression 1 92.08 High High
addiction 3 90.60 High High
Migraine 1 90.48 High High
Angina 2 78.80 Quite High
Lasting pain 1 75.12 Quite High
noradrenaline 2 48.72 Quite Low
Clonidine 1 27.52 Quite Low
Disease Link Frequency Relevance Heat
Weight Loss 3 100.00 Very High Very High Very High
Pain 5 99.60 Very High Very High Very High
Reprotox - General 1 2 99.10 Very High Very High Very High
Cluster Headache 20 98.74 Very High Very High Very High
Myocardial Infarction 8 97.36 Very High Very High Very High
Reprotox - General 2 3 96.88 Very High Very High Very High
Obesity 4 96.68 Very High Very High Very High
Cancer 3 96.32 Very High Very High Very High
Polycystic Ovary Syndrome 6 94.60 High High
Reprotox - General 3 1 92.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies are reviewed examining the influence of narcotic administration on sex-hormone levels.
Spec (examining) Regulation (influence) of sex
1) Confidence 0.60 Published 2002 Journal J Addict Dis Section Abstract Doc Link 12296501 Disease Relevance 0.77 Pain Relevance 0.24
The influence of weight reduction and female sex hormones on the regulation of lipolysis was investigated in isolated abdominal sc adipocytes from 20 obese hyperandrogenic women with polycystic ovary syndrome (PCOS).
Regulation (influence) of sex in ovary associated with weight loss, obesity and polycystic ovary syndrome
2) Confidence 0.44 Published 1999 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 10372729 Disease Relevance 0.95 Pain Relevance 0
In a prospective, case control study, we examined changes in plasma levels of sex hormones, including bio-available testosterone, in patients with acute myocardial infarction and in control subjects.
Spec (examined) Regulation (changes) of sex in plasma associated with myocardial infarction
3) Confidence 0.44 Published 2002 Journal Endocr. Res. Section Abstract Doc Link 12489566 Disease Relevance 0.58 Pain Relevance 0.15
The roles of female sex hormones, multiplicity of vascularity, and local irritants in the development of pregnancy tumors are examined.
Spec (examined) Regulation (roles) of sex associated with cancer
4) Confidence 0.44 Published 2006 Journal Quintessence Int Section Abstract Doc Link 16536149 Disease Relevance 0.41 Pain Relevance 0.09
Effects of female sex hormones on responses to CGRP, acetylcholine, and 5-HT in rat isolated arteries.
Regulation (Effects) of sex
5) Confidence 0.44 Published 2007 Journal Headache Section Title Doc Link 17445106 Disease Relevance 0.09 Pain Relevance 0.09
Other authors also found sex differences in the autonomic and cardiovascular reactivity to pain, and sex hormones have been proposed to be partly responsible for these differences.
Regulation (responsible) of sex in autonomic associated with pain
6) Confidence 0.44 Published 2009 Journal Clin. Auton. Res. Section Abstract Doc Link 19255804 Disease Relevance 0.27 Pain Relevance 0.36
OBJECTIVE: To test the hypothesis that a low-fat, vegetarian diet reduces dysmenorrhea and premenstrual symptoms by its effect on serum sex-hormone binding globulin concentration and estrogen activity.
Regulation (effect) of sex in fat associated with dismenorea
7) Confidence 0.26 Published 2000 Journal Obstet Gynecol Section Abstract Doc Link 10674588 Disease Relevance 0.17 Pain Relevance 0.17
The nature of the sex- and age-related pattern of cluster headache onset remains to be elucidated but mechanisms associated with sex hormone regulation, perhaps of hypothalamic origin, may be involved, as well as environmental factors related to lifestyle.
Regulation (regulation) of sex associated with cluster headache
8) Confidence 0.26 Published 2002 Journal Cephalalgia Section Abstract Doc Link 11972575 Disease Relevance 1.34 Pain Relevance 1.34

General Comments

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