INT82553

Context Info Confidence 0.38 First Reported 1999 Last Reported 1999 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.84 Pain Relevance 0.19

extracellular space (Sele) cell adhesion (Sele) molecular_function (Sele) cellular_component (Sele)

Sele (Rattus norvegicus)

Pain Link Frequency Relevance Heat antagonist 1 99.96 Inflammation 2 92.56 spinal inflammation 1 55.68

Disease Link Frequency Relevance Heat Overdose 1 99.04 Uveitis 9 87.16 INFLAMMATION 2 71.64 Low Back Pain 1 55.68 Disease 1 54.60

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Semiquantitative PCR revealed that E-selectin and IL-6 gene expressions were increased in rats following LPS injection, and an overdose of tamoxifen, an estrogen receptor antagonist, reversed the effect of 17beta-estradiol on E-selectin, but not its effect on IL-6.

Negative_regulation (reversed) of Regulation (effect) of E-selectin associated with antagonist and overdose

1) Confidence 0.38 Published 1999 Journal J. Immunol. Section Abstract Doc Link 10384138 Disease Relevance 0.84 Pain Relevance 0.19

General Comments

This test has worked.