INT82730

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Context Info
Confidence 0.69
First Reported 1999
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.50
Pain Relevance 2.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scn10a) plasma membrane (Scn10a) transmembrane transport (Scn10a)
Anatomy Link Frequency
DRG 2
Scn10a (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 18 99.78 Very High Very High Very High
Nerve growth factor 24 99.04 Very High Very High Very High
sodium channel 12 97.38 Very High Very High Very High
Hyperalgesia 2 86.24 High High
Peripheral nervous system 2 85.12 High High
Neuropeptide 2 71.44 Quite High
Hippocampus 2 51.84 Quite High
cerebral cortex 2 51.32 Quite High
halothane 2 20.72 Low Low
Glutamate receptor 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 18 99.78 Very High Very High Very High
Targeted Disruption 86 93.64 High High
Repression 8 89.28 High High
Hyperalgesia 2 86.24 High High
Hypertrophy 2 83.80 Quite High
Syndrome 54 52.84 Quite High
Alzheimer's Dementia 42 50.00 Quite Low
Sprains And Strains 18 44.04 Quite Low
Decapitation 2 21.60 Low Low
Autism 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hybridization signals for sodium channel subunits alphaII and beta2 displayed the most substantial enhancement in hyper-NGF mice, compared to wild-type mice DRG, and mRNA levels for alphaI, NaG, Na6, SNS/PN3, NaN, and beta1 were also greater in hyper-NGF DRG.
Transcription (levels) of SNS in DRG associated with dorsal root ganglion, nerve growth factor and sodium channel
1) Confidence 0.69 Published 1999 Journal J. Neurosci. Res. Section Abstract Doc Link 10397634 Disease Relevance 1.06 Pain Relevance 1.24
Hybridization signals for sodium channel subunits alphaII and beta2 displayed the most substantial enhancement in hyper-NGF mice, compared to wild-type mice DRG, and mRNA levels for alphaI, NaG, Na6, SNS/PN3, NaN, and beta1 were also greater in hyper-NGF DRG.
Transcription (levels) of PN3 in DRG associated with dorsal root ganglion, nerve growth factor and sodium channel
2) Confidence 0.52 Published 1999 Journal J. Neurosci. Res. Section Abstract Doc Link 10397634 Disease Relevance 1.06 Pain Relevance 1.24
Aliquots of SNs were collected at the indicated timepoints and flash frozen at ?
Transcription (collected) of SNs
3) Confidence 0.28 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1808499 Disease Relevance 0.09 Pain Relevance 0
Thus, FMRP was immunoprecipitated from WT SNs (60 min after DHPG), and the pellet was reverse transcribed and analyzed by real-time quantitative PCR (qPCR).
Spec (analyzed) Transcription (transcribed) of SNs
4) Confidence 0.22 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1808499 Disease Relevance 0.29 Pain Relevance 0.05

General Comments

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