INT82754

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Context Info
Confidence 0.39
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cck, Pomc) extracellular region (Cck, Pomc) signal transduction (Pomc)
generation of precursor metabolites and energy (Pomc) molecular_function (Pomc) cell-cell signaling (Pomc)
Cck (Rattus norvegicus)
Pomc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cholecystokinin 8 100.00 Very High Very High Very High
antagonist 2 97.84 Very High Very High Very High
Potency 2 96.30 Very High Very High Very High
Antinociceptive 1 88.20 High High
antinociception 3 86.08 High High
tail-flick 2 81.88 Quite High
Analgesic 1 79.28 Quite High
Central grey 1 76.80 Quite High
analgesia 2 75.00 Quite High
addiction 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Stress 3 80.64 Quite High
Urological Neuroanatomy 1 76.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The potency of L-365,260 and L-364,718, selective CCK(B) and CCK(A) receptor antagonists, respectively, correlated with their apparent affinities for CCK(B) receptors, suggesting that the altered sensitivity to beta-endorphin is mediated via CCK(B) receptors.
CCK Positive_regulation (mediated) of Positive_regulation (sensitivity) of beta-endorphin associated with antagonist, cholecystokinin and potency
1) Confidence 0.39 Published 1999 Journal Neurosci. Lett. Section Abstract Doc Link 10400222 Disease Relevance 0.30 Pain Relevance 1.21

General Comments

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