INT82834

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Context Info
Confidence 0.31
First Reported 1999
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.52
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cma1) extracellular region (Cma1) intracellular (Cma1)
Anatomy Link Frequency
mast cell 2
Cma1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spastic colon 1 94.36 High High
imagery 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Leukemia 7 98.72 Very High Very High Very High
Hypertension 75 98.00 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

1 94.56 High High
Functional Bowel Disorder 1 94.36 High High
Food Hypersensitivity 1 93.20 High High
Sprains And Strains 4 79.04 Quite High
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The flavonoid quercetin is one of very few molecules that inhibit RBL cell proliferation and constitutive histamine release; it also induces synthesis of rat mast cell protease (RMCP) II and accumulation of secretory granules.
Positive_regulation (induces) of Gene_expression (synthesis) of mast cell protease in mast cell associated with leukemia
1) Confidence 0.31 Published 1999 Journal Int. J. Immunopharmacol. Section Abstract Doc Link 10405873 Disease Relevance 0.75 Pain Relevance 0.09
This finding is in keeping with reports showing augmented chymase expression and increased chymostatin-inhibitable angiotensin-converting activity in SHR. [10] The increased hydrolytic effects of chymase on 125I-Ang-(1–12) metabolism in SHR was associated with a greater processing activity of ACE and NEP.
Positive_regulation (augmented) of Gene_expression (expression) of chymase associated with hypertension
2) Confidence 0.22 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3018413 Disease Relevance 0.68 Pain Relevance 0

General Comments

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