INT82876

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Context Info
Confidence 0.26
First Reported 1999
Last Reported 2010
Negated 1
Speculated 1
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 6.69
Pain Relevance 3.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (IFNAR1)
Anatomy Link Frequency
foot 1
IFNAR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 166 100.00 Very High Very High Very High
guanethidine 9 100.00 Very High Very High Very High
Gabapentin 139 99.76 Very High Very High Very High
imagery 12 98.88 Very High Very High Very High
headache 2 93.96 High High
referred pain 4 90.84 High High
diabetic neuropathy 5 85.92 High High
reflex sympathetic dystrophy 7 78.68 Quite High
Neuropathic pain 24 72.20 Quite High
anticonvulsant 11 67.00 Quite High
Disease Link Frequency Relevance Heat
Complex Regional Pain Syndromes 282 100.00 Very High Very High Very High
Pain 152 100.00 Very High Very High Very High
Charcot Marie Tooth Disease 29 98.60 Very High Very High Very High
Pressure And Volume Under Development 34 97.40 Very High Very High Very High
Osteoarthritis 4 96.20 Very High Very High Very High
Headache 2 93.96 High High
Hypesthesia 8 93.16 High High
Diabetes Mellitus 15 91.84 High High
Referred Pain 4 90.84 High High
Injury 9 86.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: The IT pain treatment with bupivacaine (with or without buprenorphine) alleviated the "refractory" pain, but affected neither the associated symptoms and signs of the CRPS-I, nor its natural evolution.
Neg (neither) Regulation (affected) of CRPS-I
1) Confidence 0.26 Published 1999 Journal Acta Anaesthesiol Scand Section Body Doc Link 10408823 Disease Relevance 0 Pain Relevance 0
In addition, a review is presented on 6 consecutive cases with CRPS I of the foot, and on 20 cases with Charcot's foot stage 0, with particular emphasis on MR imaging findings.
Spec (findings) Regulation (presented) of CRPS I in foot associated with complex regional pain syndromes, charcot marie tooth disease and imagery
2) Confidence 0.14 Published 2010 Journal Diabetol Metab Syndr Section Abstract Doc Link PMC2958966 Disease Relevance 2.25 Pain Relevance 0.39
Eight studies have been carried out into the effects of intravenous guanethidine on CRPS-I [23,46-52].
Regulation (effects) of CRPS-I associated with complex regional pain syndromes and guanethidine
3) Confidence 0.10 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2861029 Disease Relevance 0.66 Pain Relevance 0.51
Gabapentin had a mild effect on pain in CRPS I.
Regulation (effect) of CRPS I associated with complex regional pain syndromes, pain and gabapentin
4) Confidence 0.01 Published 2004 Journal BMC Neurol Section Abstract Doc Link PMC523854 Disease Relevance 1.18 Pain Relevance 1.32
Gabapentin had a mild effect on pain in patients CRPS I.
Regulation (effect) of CRPS I associated with complex regional pain syndromes, pain and gabapentin
5) Confidence 0.01 Published 2004 Journal BMC Neurol Section Body Doc Link PMC523854 Disease Relevance 1.66 Pain Relevance 1.35
Similar although not as extensive pattern of oxidative changes were found in the serum: mean serum UA and MDA concentrations and TAS value in the CRPS-I patients were higher by 16% (p=0.04), 25% (p=0.02), and 22% (p=0.05), respectively, than in the controls.
Regulation (value) of CRPS-I associated with complex regional pain syndromes
6) Confidence 0.01 Published 2008 Journal Pain Section Abstract Doc Link 18539395 Disease Relevance 0.94 Pain Relevance 0.16

General Comments

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