INT82886

Context Info Confidence 0.49 First Reported 1999 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 7 Total Number 7 Disease Relevance 3.61 Pain Relevance 1.89

plasma membrane (Mip) transmembrane transport (Mip)

Anatomy Link Frequency limb 1 parathyroid 1 T cell 1 Mip (Rattus norvegicus)

Pain Link Frequency Relevance Heat chemokine 19 100.00 cva 72 99.82 Inflammation 32 99.80 anesthesia 6 99.48 Neuritis 2 95.08 Neuropathic pain 1 91.72 Inflammatory response 3 79.08 imagery 3 77.44 cytokine 10 76.76 reflex sympathetic dystrophy 2 75.00

Disease Link Frequency Relevance Heat Subarachnoid Hemorrhage 70 99.82 INFLAMMATION 33 99.80 Hypercalcemia 8 99.34 Congenital Anomalies 2 97.96 Adhesions 18 96.04 Recurrence 2 95.44 Immunization 2 95.20 Experimental Autoimmune Neuritis 2 95.08 Disease 5 93.52 Neuropathic Pain 1 91.72

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Interferon-gamma-inducible protein (IP)-10, monocyte chemotactic protein (MCP)-1, macrophage inflammatory protein (MIP)-1alpha, the regulated upon activation normal T cell expressed and secreted chemokine (RANTES), and lymphotactin were analyzed on days 0 (pre-immunization), 7 (preclinical stage), 10 (disease onset), 13 (clinical progression), 17 (disease peak), as well as on days 20, 24, and 34 post-immunization (p.i.)

Positive_regulation (regulated) of MIP in T cell associated with chemokine, inflammation, immunization and disease

1) Confidence 0.49 Published 1999 Journal J. Neuroimmunol. Section Abstract Doc Link 10408979 Disease Relevance 0.73 Pain Relevance 0.44

The technical aspects of this procedure are described, and the results obtained in 255 patients who underwent MIP are compared with those of 401 patients who underwent conventional bilateral cervical exploration under general anesthesia.

Positive_regulation (underwent) of MIP associated with anesthesia

2) Confidence 0.40 Published 2004 Journal World J Surg Section Abstract Doc Link 15517494 Disease Relevance 0 Pain Relevance 0.19

Usage of general vs local anesthesia with intravenous sedation was 46% and 49%, respectively, in patients w ho underwent MIP; 46% were dismissed as outpatients, 49% had single-night stays.

Positive_regulation (underwent) of MIP

3) Confidence 0.22 Published 2005 Journal Arch Surg Section Body Doc Link 15897443 Disease Relevance 0 Pain Relevance 0

Changes in the management of primary HPT have occurred since introducing MIP including localization, anesthesia, intraoperative parathyroid hormone monitoring, and indications for parathyroidectomy.

Positive_regulation (introducing) of MIP in parathyroid associated with anesthesia and hypercalcemia

4) Confidence 0.22 Published 2005 Journal Arch Surg Section Abstract Doc Link 15897443 Disease Relevance 0.46 Pain Relevance 0.10

Furthermore, we observed marked SAH-induced upregulation of the chemokines MIP-1?

Positive_regulation (upregulation) of MIP associated with chemokine and cva

5) Confidence 0.20 Published 2010 Journal Crit Care Section Body Doc Link PMC2945141 Disease Relevance 1.64 Pain Relevance 0.67

The results uphold the hypothesis that a MIP initially not involving limb movement is effective for CRPS1 and support the involvement of cortical abnormalities in the development of this disorder.

Positive_regulation (effective) of MIP in limb associated with congenital anomalies

6) Confidence 0.17 Published 2004 Journal Pain Section Abstract Doc Link 15109523 Disease Relevance 0.78 Pain Relevance 0.49

Capdevila and colleagues[16] reported that patients with low P0.1 and P0.1/MIP failed extubation, Mergoni and colleagues[30] reported excellent prediction of success in weaning using P0.1/MIP, while Del Rosario[31] found similar P0.1/MIP values in patients with weaning success and failure.

Positive_regulation (using) of MIP

7) Confidence 0.06 Published 2008 Journal Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine Section Body Doc Link PMC2760915 Disease Relevance 0 Pain Relevance 0

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