INT82900

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Context Info
Confidence 0.49
First Reported 1999
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.86
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (BAX) cytosol (BAX) mitochondrion (BAX)
endoplasmic reticulum (BAX) nucleus (BAX) cytoplasm (BAX)
Anatomy Link Frequency
apoptotic cells 2
BAX (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 46 97.92 Very High Very High Very High
Dismenorea 2 67.08 Quite High
cytokine 3 28.08 Quite Low
pain pelvic 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 44 100.00 Very High Very High Very High
Endometriosis 48 97.92 Very High Very High Very High
Death 8 88.40 High High
Dysmenorrhea 1 67.08 Quite High
Hypoxia 1 63.24 Quite High
Disease 5 50.72 Quite High
Cancer 1 13.52 Low Low
Reprotox - General 3 4 5.00 Very Low Very Low Very Low
Reprotox - General 1 2 5.00 Very Low Very Low Very Low
Gynecological Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This marked increase was associated with a decrease in the intensity of the Bcl-2 immunostaining and an increase in the intensity of Bax and Bcl-x immunostaining.
Positive_regulation (increase) of Transcription (intensity) of Bax
1) Confidence 0.49 Published 1999 Journal Biol. Reprod. Section Abstract Doc Link 10411527 Disease Relevance 0.41 Pain Relevance 0.07
Curiously, we detected that both bax mRNA abundance and apoptotic cells were increased in early secretory phase in eutopic endometrium from women with endometriosis but not from normal women.
Positive_regulation (increased) of Transcription (abundance) of bax in apoptotic cells associated with endometriosis and apoptosis
2) Confidence 0.48 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1262771 Disease Relevance 1.45 Pain Relevance 0.22

General Comments

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