INT82930

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Context Info
Confidence 0.26
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.07
Pain Relevance 0.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F3) aging (F3) cytoplasm (F3)
Anatomy Link Frequency
blood 1
plaque 1
F3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spinal inflammation 2 94.88 High High
Angina 2 94.60 High High
Inflammation 2 75.00 Quite High
analgesia 1 74.00 Quite High
anesthesia 1 73.56 Quite High
Disease Link Frequency Relevance Heat
Myocardial Infarction 1 95.84 Very High Very High Very High
Cv General 3 Under Development 2 94.60 High High
Coronary Artery Disease 4 88.96 High High
Acute Coronary Syndrome 3 82.40 Quite High
Syndrome 1 78.96 Quite High
Stress 4 78.60 Quite High
Atherosclerosis 8 77.04 Quite High
Sepsis 1 76.36 Quite High
Eclampsia 1 76.04 Quite High
Malignant Neoplastic Disease 1 75.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BACKGROUND: Tissue factor, the main initiator of blood coagulation, is released into the bloodstream when vessel damage occurs.
Localization (released) of Tissue factor in blood
1) Confidence 0.26 Published 2006 Journal Joint Bone Spine Section Abstract Doc Link 16730212 Disease Relevance 0.15 Pain Relevance 0.21
It secretes tissue factor into extravascular tissues, and insulates those tissues from the hepatic enzymes, so that tissue disruption exposes tissue factor to the enzymatic interaction and activates tissue repair.
Localization (secretes) of tissue factor
2) Confidence 0.01 Published 2010 Journal Cardiovasc Hematol Disord Drug Targets Section Abstract Doc Link 20443776 Disease Relevance 0.95 Pain Relevance 0.15
Possible reasons for this activation are an activation of the contact phase factor XII system and the release of tissue factor both from the ruptured plaque and from stimulated monocytes.
Localization (release) of tissue factor in plaque
3) Confidence 0.01 Published 1999 Journal Z Kardiol Section Abstract Doc Link 10413853 Disease Relevance 0.97 Pain Relevance 0.19

General Comments

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