INT82969

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Context Info
Confidence 0.02
First Reported 1999
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.28
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

ATPase activity (Hltf) nucleus (Hltf) helicase activity (Hltf)
DNA binding (Hltf) ligase activity (Hltf)
Hltf (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 3 98.66 Very High Very High Very High
dexamethasone 22 93.40 High High
Glutamate 5 92.40 High High
Dopamine 4 91.84 High High
Kappa opioid receptor 2 91.12 High High
dopamine receptor 1 89.76 High High
corticosteroid 1 88.56 High High
Inflammation 10 83.68 Quite High
agonist 3 82.56 Quite High
antagonist 2 81.56 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 15 83.68 Quite High
Rheumatoid Arthritis 4 65.44 Quite High
Disease Progression 1 61.44 Quite High
Multiple Sclerosis 50 40.32 Quite Low
Demyelinating Disease 1 38.56 Quite Low
Central Nervous System Disease 6 36.56 Quite Low
Diabetes Mellitus 1 29.76 Quite Low
Muscular Atrophy 1 29.28 Quite Low
Osteoporosis 1 28.64 Quite Low
Disease 11 22.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Changes in immediate early and neuropeptide gene expression that result from activation of these cascades are mediated by such nuclear transcription factors as phosphorylated cyclase response element-binding protein.
Positive_regulation (mediated) of cyclase response element-binding protein associated with neuropeptide
1) Confidence 0.02 Published 1999 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 10415647 Disease Relevance 0 Pain Relevance 0.75
B driven gene expression without inducing GC response element (GRE) dependent genes [15].
Neg (without) Positive_regulation (inducing) of response element
2) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2781169 Disease Relevance 0.28 Pain Relevance 0.28

General Comments

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