INT82983

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Context Info
Confidence 0.66
First Reported 1999
Last Reported 1999
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 5
Disease Relevance 0.17
Pain Relevance 1.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cartpt) extracellular region (Cartpt)
Anatomy Link Frequency
shell 2
brain 1
Cartpt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cocaine 21 99.48 Very High Very High Very High
Enkephalin 4 99.18 Very High Very High Very High
Neurotransmitter 4 98.60 Very High Very High Very High
drug abuse 1 97.64 Very High Very High Very High
amygdala 7 90.92 High High
Nucleus accumbens 2 89.84 High High
Dopamine 8 88.84 High High
dopamine receptor 1 78.24 Quite High
Dynorphin 4 75.00 Quite High
Opioid 2 49.72 Quite Low
Disease Link Frequency Relevance Heat
Drug Dependence 1 97.64 Very High Very High Very High
Cocaine Dependence 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have noted differences between male and female rats in the mesolimbic mRNA expression of CART that might be relevant for gender differences apparent in drug abuse.
Transcription (expression) of CART associated with drug abuse
1) Confidence 0.66 Published 1999 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 10415667 Disease Relevance 0.17 Pain Relevance 0.92
Mesolimbic gender differences in peptide CART mRNA expression: effects of cocaine.
Transcription (expression) of CART associated with enkephalin and cocaine
2) Confidence 0.53 Published 1999 Journal Neuroreport Section Title Doc Link 10599860 Disease Relevance 0 Pain Relevance 0.32
A gender difference was noted in the accumbens shell during basal conditions; male rats expressed higher levels of CART mRNA than both female groups.
Transcription (levels) of CART in shell
3) Confidence 0.53 Published 1999 Journal Neuroreport Section Abstract Doc Link 10599860 Disease Relevance 0 Pain Relevance 0.21
We analyzed the CART mRNA expression in mesolimbic brain areas of male and ovariectomized 17beta-estradiol- (30 microg) and vehicle-treated female rats.
Spec (analyzed) Transcription (expression) of CART in brain
4) Confidence 0.53 Published 1999 Journal Neuroreport Section Abstract Doc Link 10599860 Disease Relevance 0 Pain Relevance 0.19
A gender difference was noted in the accumbens shell during basal conditions; male rats expressed higher levels of CART mRNA than both female groups.
Transcription (expressed) of CART in shell
5) Confidence 0.53 Published 1999 Journal Neuroreport Section Abstract Doc Link 10599860 Disease Relevance 0 Pain Relevance 0.22

General Comments

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