INT82990

Context Info Confidence 0.02 First Reported 1999 Last Reported 1999 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.42 Pain Relevance 0.99

nucleoplasm (POLR3D) nucleus (POLR3D) DNA binding (POLR3D)

Anatomy Link Frequency brains 1 POLR3D (Homo sapiens)

Pain Link Frequency Relevance Heat Dopamine 7 100.00 Kappa opioid receptor 3 99.80 cocaine 12 97.96 addiction 2 97.96 Endogenous opioid 1 95.40 Nucleus accumbens 3 88.16 amygdala 1 33.92 Opioid 1 28.64

Disease Link Frequency Relevance Heat Cocaine Dependence 2 97.96 Overdose 5 97.64 Delirium 1 40.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We have used in vitro autoradiography and ligand binding to map D3 DA and kappa opioid receptors in the human brains of cocaine-overdose victims.

D3 DA Binding (binding) of in brains associated with dopamine, kappa opioid receptor, overdose and cocaine

1) Confidence 0.02 Published 1999 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 10415668 Disease Relevance 0.42 Pain Relevance 0.99

General Comments

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