INT83093

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Context Info
Confidence 0.51
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.44
Pain Relevance 1.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) endoplasmic reticulum (BDKRB1)
IL1B (Homo sapiens)
BDKRB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
bradykinin 26 99.46 Very High Very High Very High
antagonist 2 95.96 Very High Very High Very High
cytokine 2 94.00 High High
Inflammation 6 85.12 High High
Pain 2 79.96 Quite High
agonist 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Pain 2 79.96 Quite High
INFLAMMATION 6 79.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interleukin-1beta (IL-1beta; 500 pg/ml) also increased B1R (4- to 6-fold).
IL-1beta Positive_regulation (increased) of B1R
1) Confidence 0.51 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 10419551 Disease Relevance 0.23 Pain Relevance 0.84
DesArg(10)KD and BK synergistically increased B1R (9-fold), which was further increased by inclusion of IL-1beta (36-fold).
IL-1beta Positive_regulation (increased) of B1R associated with bradykinin
2) Confidence 0.45 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 10419551 Disease Relevance 0.20 Pain Relevance 0.81

General Comments

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