INT83199

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.78
First Reported 1997
Last Reported 2011
Negated 9
Speculated 10
Reported most in Abstract
Documents 193
Total Number 203
Disease Relevance 100.72
Pain Relevance 51.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nos3) aging (Nos3) Golgi apparatus (Nos3)
cytoplasm (Nos3) signal transduction (Nos3) oxidoreductase activity (Nos3)
Anatomy Link Frequency
neuronal 10
endothelial cells 9
lungs 8
dorsal horns 7
sciatic nerves 7
Nos3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 1094 100.00 Very High Very High Very High
Neuronal nitric oxide synthase 31 100.00 Very High Very High Very High
Dorsal horn 384 99.96 Very High Very High Very High
ischemia 1439 99.92 Very High Very High Very High
cINOD 136 99.92 Very High Very High Very High
Angina 37 99.92 Very High Very High Very High
calcitonin gene related peptide 6 99.92 Very High Very High Very High
dorsal root ganglion 33 99.84 Very High Very High Very High
agonist 221 99.76 Very High Very High Very High
Sciatic nerve 79 99.68 Very High Very High Very High
Disease Link Frequency Relevance Heat
INFLAMMATION 1270 100.00 Very High Very High Very High
Shock 22 100.00 Very High Very High Very High
Cv Unclassified Under Development 1446 99.92 Very High Very High Very High
Cv General 3 Under Development 50 99.92 Very High Very High Very High
Hypoxia 291 99.84 Very High Very High Very High
Ganglion Cysts 40 99.84 Very High Very High Very High
Acute Coronary Syndrome 18 99.84 Very High Very High Very High
Apoptosis 127 99.68 Very High Very High Very High
Autoimmune Disease 8 99.68 Very High Very High Very High
Atherosclerotic Plaque 8 99.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, Western blot analysis showed that eNOS expression in the mesentery was increased in the Estrogen group compared with the Placebo group.
Gene_expression (expression) of eNOS in mesentery
1) Confidence 0.78 Published 2004 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 15231501 Disease Relevance 0.53 Pain Relevance 0.07
This study examined the expression of constitutive endothelial nitric oxide synthase (eNOS) and inducible NOS (iNOS) in the sciatic nerve of Lewis rats with experimental autoimmune neuritis (EAN).
Spec (examined) Gene_expression (expression) of eNOS in sciatic nerve associated with experimental autoimmune neuritis, sciatic nerve and neuritis
2) Confidence 0.77 Published 2002 Journal J. Neuroimmunol. Section Abstract Doc Link 12020959 Disease Relevance 0.57 Pain Relevance 0.71
This study examined the expression of constitutive endothelial nitric oxide synthase (eNOS) and inducible NOS (iNOS) in the sciatic nerve of Lewis rats with experimental autoimmune neuritis (EAN).
Spec (examined) Gene_expression (expression) of constitutive endothelial nitric oxide synthase in sciatic nerve associated with experimental autoimmune neuritis, sciatic nerve and neuritis
3) Confidence 0.77 Published 2002 Journal J. Neuroimmunol. Section Abstract Doc Link 12020959 Disease Relevance 0.57 Pain Relevance 0.70
The expression of caveolin-1 and the related molecule endothelial nitric oxide synthase (eNOS) was analyzed in the sciatic nerves of Lewis rats with experimental autoimmune neuritis (EAN).
Spec (analyzed) Gene_expression (expression) of eNOS in sciatic nerves associated with experimental autoimmune neuritis, sciatic nerve and neuritis
4) Confidence 0.76 Published 2006 Journal Brain Res. Section Abstract Doc Link 16806125 Disease Relevance 0.56 Pain Relevance 0.62
Chronic exercise upregulates endothelial nitric oxide synthase (eNOS) gene expression.
Gene_expression (expression) of eNOS
5) Confidence 0.75 Published 2002 Journal J. Biomed. Sci. Section Abstract Doc Link 11914582 Disease Relevance 0 Pain Relevance 0.07
The mucosal expression levels of eNOS and iNOS but not nNOS mRNAs were enhanced in arthritic rats compared with normal rats.
Gene_expression (expression) of eNOS associated with arthritis
6) Confidence 0.75 Published 2009 Journal J. Pharmacol. Sci. Section Abstract Doc Link 19881222 Disease Relevance 1.14 Pain Relevance 0.20
Our results show that chronic exercise increases both iNOS and eNOS gene expression in endothelium.
Gene_expression (expression) of eNOS gene in endothelium
7) Confidence 0.75 Published 2002 Journal J. Biomed. Sci. Section Abstract Doc Link 11914582 Disease Relevance 0 Pain Relevance 0.08
In the AdeNOS-treated rats, the local expression of eNOS protein was confirmed by immunohistochemistry, and eNOS production was measured by in vivo microdialysis.
Gene_expression (expression) of eNOS
8) Confidence 0.73 Published 2001 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 11458677 Disease Relevance 0 Pain Relevance 0.08
Biopsy mucosal samples were taken for expression of constitutive NO-synthase (cNOS) and inducible NOS (iNOS) by reverse transcriptase-polymerase chain reaction (RT-PCR).
Gene_expression (expression) of cNOS
9) Confidence 0.71 Published 2002 Journal J. Pineal Res. Section Abstract Doc Link 12074098 Disease Relevance 1.04 Pain Relevance 0.11
In this study, we investigated mucosal expression of ET-1, interleukin-4 (IL-4), and the activity of constitutive nitric oxide synthase (cNOS) during indomethacin-induced gastric mucosal injury, and evaluated the effect of antiulcer agents on this process.
Spec (investigated) Gene_expression (expression) of cNOS associated with injury
10) Confidence 0.69 Published 1999 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 10424717 Disease Relevance 0.43 Pain Relevance 0.10
Thus for the first time we showed that mesenteric eNOS overexpression could explain at least partly why chronic estrogen treatment suppressed the enhanced cardiovascular responses to psychological stress in the ovariectomized rat.
Gene_expression (overexpression) of eNOS associated with stress
11) Confidence 0.68 Published 2004 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 15231501 Disease Relevance 0.54 Pain Relevance 0.07
These data suggest that ROS may be involved in the scavenging of NO in these animals as eNOS protein expression levels were not significantly different in the experimental groups compared to Chow fed rats (Figure 8).
Gene_expression (expression) of eNOS
12) Confidence 0.67 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2887873 Disease Relevance 0.68 Pain Relevance 0.12
However, iNOS was found mainly in inflammatory macrophages in sciatic nerve EAN lesions.These findings suggest that, depending on the stage of peripheral nervous system autoimmune disease, the increased expressions of both eNOS and iNOS might be involved in either the production of detrimental effects during the induction stage of EAN or in the recovery from EAN paralysis.
Gene_expression (expressions) of eNOS in sciatic nerve associated with autoimmune disease, peripheral nervous system, inflammation, sciatic nerve, neuritis and paralysis
13) Confidence 0.67 Published 2002 Journal J. Neuroimmunol. Section Abstract Doc Link 12020959 Disease Relevance 1.07 Pain Relevance 1.03
Western blot analysis showed that both eNOS and iNOS expressions in the sciatic nerves of rats increased significantly during the peak stage of EAN, but declined thereafter.
Gene_expression (expressions) of eNOS in sciatic nerves associated with sciatic nerve and neuritis
14) Confidence 0.67 Published 2002 Journal J. Neuroimmunol. Section Abstract Doc Link 12020959 Disease Relevance 0.71 Pain Relevance 0.82
These alterations with the exception of eNOS expression were significantly blocked by benidipine treatment.
Gene_expression (expression) of eNOS
15) Confidence 0.67 Published 2002 Journal Diabetologia Section Body Doc Link 11914746 Disease Relevance 0.06 Pain Relevance 0
The pattern of eNOS expression over the course of EAN largely matched that of caveolin-1.
Gene_expression (expression) of eNOS associated with neuritis
16) Confidence 0.66 Published 2006 Journal Brain Res. Section Abstract Doc Link 16806125 Disease Relevance 0.78 Pain Relevance 0.92
The expression of caveolin-1 and the related molecule endothelial nitric oxide synthase (eNOS) was analyzed in the sciatic nerves of Lewis rats with experimental autoimmune neuritis (EAN).
Spec (analyzed) Gene_expression (expression) of endothelial nitric oxide synthase in sciatic nerves associated with experimental autoimmune neuritis, sciatic nerve and neuritis
17) Confidence 0.66 Published 2006 Journal Brain Res. Section Abstract Doc Link 16806125 Disease Relevance 0.56 Pain Relevance 0.61
The aim of this work was therefore to study the expression of nNOS, iNOS and eNOS in the dorsal horns of monoarthritic rats, and the modifications in NOS expression induced by pharmacological blockade of spinal cord NMDA receptors.
Gene_expression (expression) of eNOS in dorsal horns associated with nmda receptor and spinal cord
18) Confidence 0.66 Published 2007 Journal Arthritis Res Ther Section Abstract Doc Link PMC2206346 Disease Relevance 0.60 Pain Relevance 0.90
Chronic exercise upregulates endothelial nitric oxide synthase (eNOS) gene expression.
Gene_expression (expression) of endothelial nitric oxide synthase
19) Confidence 0.66 Published 2002 Journal J. Biomed. Sci. Section Abstract Doc Link 11914582 Disease Relevance 0 Pain Relevance 0.07
Chronic exercise increases both inducible and endothelial nitric oxide synthase gene expression in endothelial cells of rat aorta.
Gene_expression (expression) of endothelial nitric oxide synthase in endothelial cells
20) Confidence 0.66 Published 2002 Journal J. Biomed. Sci. Section Title Doc Link 11914582 Disease Relevance 0 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox