INT83217

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Context Info
Confidence 0.16
First Reported 1999
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 0
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Nr5a2) nucleus (Nr5a2) DNA binding (Nr5a2)
cytoplasm (Nr5a2)
Nr5a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 10 97.52 Very High Very High Very High
Clonidine 2 87.16 High High
gABA 6 50.00 Quite Low
anesthesia 2 10.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increase was shown in both the cytoskeleton (beta2(54) and beta2(56) subtypes) and the cell membrane (beta2(54) and beta3 subtypes).
Positive_regulation (increase) of beta2
1) Confidence 0.16 Published 2003 Journal Acta Anaesthesiol Scand Section Body Doc Link 12631044 Disease Relevance 0 Pain Relevance 0
CONCLUSION: The difference between propofol and GABA at the GABA(A) receptor was shown to take place in the membrane, where the beta2(54) was increased by propofol and instead the beta2(56) subtype was increased by GABA.
Positive_regulation (increased) of beta2
2) Confidence 0.16 Published 2003 Journal Acta Anaesthesiol Scand Section Body Doc Link 12631044 Disease Relevance 0 Pain Relevance 0
The net peptide secretion results from the activation of the beta2-isoreceptor type.
Positive_regulation (activation) of beta2-isoreceptor
3) Confidence 0.04 Published 1999 Journal J. Endocrinol. Section Abstract Doc Link 10425466 Disease Relevance 0 Pain Relevance 0.23
Because terbutaline but not dobutamine or BRL 37,344 (10(-5) M) induced significant GLP-1 and PYY secretions (135+/-30 and 305+/-39 fmol/8 min respectively), isoproterenol-induced secretions are suggested to result mainly from stimulation of the beta2-isoreceptor type.
Positive_regulation (stimulation) of beta2-isoreceptor
4) Confidence 0.04 Published 1999 Journal J. Endocrinol. Section Abstract Doc Link 10425466 Disease Relevance 0 Pain Relevance 0.26

General Comments

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