INT83274

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Context Info
Confidence 0.11
First Reported 1999
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.71
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itga2b)
Anatomy Link Frequency
platelet 4
Itga2b (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 1 90.72 High High
agonist 10 68.88 Quite High
cytokine 6 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thrombosis 69 100.00 Very High Very High Very High
Infarction 1 99.00 Very High Very High Very High
Myocardial Infarction 5 94.36 High High
Adhesions 16 91.92 High High
Death 1 91.88 High High
Recurrence 1 91.60 High High
Cv General 3 Under Development 1 90.72 High High
Hypothermia 92 85.20 High High
Endotoxemia 42 67.92 Quite High
Sepsis 32 57.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Captopril administration reduces thrombus formation and surface expression of platelet glycoprotein IIb/IIa in early postmyocardial infarction stage.
Negative_regulation (reduces) of Gene_expression (expression) of platelet glycoprotein IIb/IIa in platelet associated with infarction and thrombosis
1) Confidence 0.11 Published 1999 Journal Arterioscler. Thromb. Vasc. Biol. Section Title Doc Link 10428581 Disease Relevance 0.83 Pain Relevance 0.09
Of interest, spontaneous platelet GPIIb-IIIa expression did not increase but even slightly decreased after endotoxin exposure, and thrombin-stimulation of endotoxin-exposed platelets also induced an only slight but not significant elevation of expression.
Neg (not) Negative_regulation (decreased) of Gene_expression (expression) of GPIIb-IIIa in platelets
2) Confidence 0.04 Published 2006 Journal Crit Care Section Body Doc Link PMC1751084 Disease Relevance 0.88 Pain Relevance 0.07
Flow cytometric analysis of P-selectin, glycoprotein IIb-IIIa and CD107a expression
Negative_regulation (analysis) of Gene_expression (expression) of glycoprotein IIb-IIIa
3) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1751084 Disease Relevance 0 Pain Relevance 0

General Comments

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