INT83354

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Context Info
Confidence 0.43
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.69
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GSR) mitochondrion (GSR) small molecule metabolic process (GSR)
oxidoreductase activity (GSR) cytoplasm (GSR)
GSR (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 1 94.68 High High
Inflammation 3 94.08 High High
cytokine 2 88.52 High High
cINOD 1 57.96 Quite High
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 98.74 Very High Very High Very High
INFLAMMATION 6 94.08 High High
Asthma 4 77.32 Quite High
Occupational Lung Diseases 1 62.52 Quite High
Cirrhosis 2 17.20 Low Low
Liver Disease 5 5.00 Very Low Very Low Very Low
Hepatotoxicity 2 5.00 Very Low Very Low Very Low
Ulcers 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The GC-independent repression of AP-1 and NF-kappa B activities was further demonstrated by overexpressing a ligand-binding deficient GR mutant.
Positive_regulation (overexpressing) of GR Binding (binding) of associated with repression
1) Confidence 0.43 Published 1999 Journal Gene Ther. Section Abstract Doc Link 10435109 Disease Relevance 0.69 Pain Relevance 0.31
Accordingly, we presumed that the extract was capable of increasing the activities of GPx and GR, which resulted in enhanced intracellular glutathione cycling.
Positive_regulation (increasing) of GR Binding (activities) of
2) Confidence 0.20 Published 2010 Journal Advances in Pharmacological Sciences Section Body Doc Link PMC3005810 Disease Relevance 0 Pain Relevance 0

General Comments

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