INT83375

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.58
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 9
Disease Relevance 1.57
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CALM3) small molecule metabolic process (CALM3) carbohydrate metabolic process (CALM3)
cytoplasm (CALM3) cytosol (CALM3) signal transduction (CALM3)
CALM3 (Homo sapiens)
Pain Link Frequency Relevance Heat
TRP channel 28 99.92 Very High Very High Very High
adenocard 7 93.52 High High
addiction 14 90.68 High High
agonist 21 90.12 High High
palliative 1 81.84 Quite High
Spinal cord 2 77.88 Quite High
Bile 2 70.32 Quite High
imagery 8 5.00 Very Low Very Low Very Low
qutenza 7 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ependymoma 37 99.44 Very High Very High Very High
Chordoma 9 91.56 High High
Carcinoma 14 88.96 High High
Disease 3 87.32 High High
Recurrence 3 86.40 High High
Glioma 4 82.72 Quite High
Cancer 16 75.00 Quite High
Pancreatic Cancer 2 73.28 Quite High
Uterine Cancer 1 56.88 Quite High
Ovarian Cancer 1 54.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We describe two cases of MPE with cytokeratin (AE1 AE3, CAM 5.2, Cytokeratin 7 and cytokeratin 20) expression.


Gene_expression (expression) of CAM associated with ependymoma
1) Confidence 0.58 Published 2008 Journal Diagn Pathol Section Abstract Doc Link PMC2584038 Disease Relevance 0.94 Pain Relevance 0.04
Coexpression of CaM1234 abolished TRPC6 activation secondary to Gq protein-coupled receptor activation or diacylglycerol application [31], [32] and strongly decreased activation of the adenosine diphosphoribose-sensitive channel TRPM2 [33], [34].
Gene_expression (Coexpression) of CaM1234 associated with adenocard
2) Confidence 0.24 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.10
We measured the current increase on adding Ca2+ (2 mM) in HEK293 cells expressing YFP (not shown) or TRPV4 alone (control), or TRPV4 together with CaM or CaM mutants (Fig. 1F).
Gene_expression (expressing) of CaM
3) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.08
CaM or the CaM mutants had no effect on spontaneous currents, or currents activated by 4?
Gene_expression (mutants) of CaM
4) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.08
We measured the current increase on adding Ca2+ (2 mM) in HEK293 cells expressing YFP (not shown) or TRPV4 alone (control), or TRPV4 together with CaM or CaM mutants (Fig. 1F).
Gene_expression (expressing) of CaM
5) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.08
CaM or the CaM mutants had no effect on spontaneous currents, or currents activated by 4?
Gene_expression (mutants) of CaM
6) Confidence 0.21 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.08
To assess whether this finding is functionally relevant, we tested the effect of overexpression of CaM and CaM mutants on TRPV4 activity.
Gene_expression (overexpression) of CaM
7) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.09
To assess whether this finding is functionally relevant, we tested the effect of overexpression of CaM and CaM mutants on TRPV4 activity.
Gene_expression (overexpression) of CaM
8) Confidence 0.19 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2867956 Disease Relevance 0 Pain Relevance 0.09
Some other markers comprise in addition to sialyl-Lewis(a) partially the non-sialylated Lewis(a) antigen (CA 195, CAM 43, CA 494) or are less related (CAM 17.1).
Gene_expression (comprise) of CAM 43
9) Confidence 0.08 Published 1999 Journal Ann. Oncol. Section Abstract Doc Link 10436809 Disease Relevance 0.63 Pain Relevance 0.15

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox