INT83415

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Context Info
Confidence 0.01
First Reported 1999
Last Reported 1999
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk1) endosome (Ntrk1) aging (Ntrk1)
plasma membrane (Ntrk1) cytoplasm (Ntrk1) signal transducer activity (Oprm1)
Oprm1 (Rattus norvegicus)
Ntrk1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 7 100.00 Very High Very High Very High
agonist 4 100.00 Very High Very High Very High
opioid receptor 3 100.00 Very High Very High Very High
antagonist 1 99.20 Very High Very High Very High
orphanin 6 98.44 Very High Very High Very High
Enkephalin 1 75.68 Quite High
mu opioid receptor 1 69.72 Quite High
narcan 3 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicate that TRK-820 acts as a full agonist for the kappa-opioid receptor, a partial agonist for the mu-opioid receptor and a low-affinity antagonist for the nociceptin receptor.
mu-opioid receptor Spec (partial) Binding (agonist) of TRK-820 associated with orphanin, antagonist, kappa opioid receptor, agonist and opioid receptor
1) Confidence 0.01 Published 1999 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10440101 Disease Relevance 0 Pain Relevance 0.96

General Comments

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