INT83464

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Context Info
Confidence 0.46
First Reported 1998
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 3.71
Pain Relevance 1.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Icam1) cell adhesion (Icam1) plasma membrane (Icam1)
Anatomy Link Frequency
C3A 2
Icam1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 30 99.80 Very High Very High Very High
ischemia 9 99.32 Very High Very High Very High
Inflammation 21 85.08 High High
anesthesia 3 74.32 Quite High
Pain 4 25.00 Low Low
Inflammatory mediators 2 20.24 Low Low
fibrosis 5 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 24 100.00 Very High Very High Very High
Cv General 3 Under Development 12 99.80 Very High Very High Very High
Coronary Artery Disease 8 99.32 Very High Very High Very High
Emergencies 2 91.68 High High
Angina 18 90.08 High High
Cirrhosis 2 85.08 High High
Injury 9 78.80 Quite High
Stress 2 77.84 Quite High
Nash(non-alcoholic Steatohepatitis) 12 67.80 Quite High
Disease 5 66.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum sTM and ICAM-1 levels were also significantly increased after reperfusion (sTM: 3.3+/-0.8 to 5.1+/-1.7 FU/ml, p=0.0001; ICAM-1: 271.9+/-86.3 to 515.0+/-157.8 FU/ml, p=0.0001).
Positive_regulation (increased) of Localization (levels) of ICAM-1
1) Confidence 0.46 Published 2008 Journal Int. J. Mol. Med. Section Abstract Doc Link 18097619 Disease Relevance 0.40 Pain Relevance 0.20
The purpose of our study was to verify whether myocardial ischemia occurring during angina episodes results in the release of the soluble adhesion molecules, L-selectin, E-selectin, and intracellular adhesion molecule-1 (ICAM-1), into the circulation.
Spec (whether) Positive_regulation (results) of Localization (release) of ICAM-1 associated with angina, coronary artery disease, ischemia and adhesions
2) Confidence 0.11 Published 1998 Journal Heart Vessels Section Abstract Doc Link 10442400 Disease Relevance 1.53 Pain Relevance 0.59
Increased release of the soluble form of the adhesion molecules L-selectin and ICAM-1 but not E-selectin during attacks of angina pectoris.
Positive_regulation (Increased) of Localization (release) of ICAM-1 associated with angina and adhesions
3) Confidence 0.11 Published 1998 Journal Heart Vessels Section Title Doc Link 10442400 Disease Relevance 1.30 Pain Relevance 0.50
Protein levels of sICAM released by C3A cells increased in a dose-dependent manner (Figure 4(a)).
Positive_regulation (increased) of Localization (released) of sICAM in C3A
4) Confidence 0.09 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2817554 Disease Relevance 0.49 Pain Relevance 0.11

General Comments

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