INT83465

Context Info Confidence 0.09 First Reported 1998 Last Reported 1998 Negated 0 Speculated 1 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 2.81 Pain Relevance 1.08

extracellular space (Sele) cell adhesion (Sele) molecular_function (Sele) cellular_component (Sele)

Sele (Rattus norvegicus)

Pain Link Frequency Relevance Heat Angina 30 99.80 ischemia 8 99.32 Pain 4 25.00

Disease Link Frequency Relevance Heat Adhesions 18 100.00 Cv General 3 Under Development 12 99.80 Coronary Artery Disease 8 99.32 Emergencies 2 87.92 Angina 18 86.32 Stress 2 74.08 Pain 4 25.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Increased release of the soluble form of the adhesion molecules L-selectin and ICAM-1 but not E-selectin during attacks of angina pectoris.

Positive_regulation (Increased) of Localization (release) of E-selectin associated with angina and adhesions

1) Confidence 0.09 Published 1998 Journal Heart Vessels Section Title Doc Link 10442400 Disease Relevance 1.31 Pain Relevance 0.50

The purpose of our study was to verify whether myocardial ischemia occurring during angina episodes results in the release of the soluble adhesion molecules, L-selectin, E-selectin, and intracellular adhesion molecule-1 (ICAM-1), into the circulation.

Spec (whether) Positive_regulation (results) of Localization (release) of E-selectin associated with angina, coronary artery disease, ischemia and adhesions

2) Confidence 0.09 Published 1998 Journal Heart Vessels Section Abstract Doc Link 10442400 Disease Relevance 1.50 Pain Relevance 0.57

General Comments

This test has worked.