INT83466

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Context Info
Confidence 0.08
First Reported 1998
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 3.44
Pain Relevance 1.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Sell) plasma membrane (Sell)
Sell (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 30 99.50 Very High Very High Very High
ischemia 8 99.02 Very High Very High Very High
Inflammation 7 94.40 High High
Pain 9 93.52 High High
IPN 1 75.00 Quite High
analgesia 1 71.52 Quite High
opioid receptor 1 70.60 Quite High
Opioid 1 65.52 Quite High
Disease Link Frequency Relevance Heat
Adhesions 22 100.00 Very High Very High Very High
Cv General 3 Under Development 12 99.50 Very High Very High Very High
Coronary Artery Disease 8 99.02 Very High Very High Very High
INFLAMMATION 3 94.40 High High
Emergencies 2 86.96 High High
Angina 18 85.36 High High
Inflammatory Pain 1 75.00 Quite High
Stress 2 73.12 Quite High
Pain 4 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The purpose of our study was to verify whether myocardial ischemia occurring during angina episodes results in the release of the soluble adhesion molecules, L-selectin, E-selectin, and intracellular adhesion molecule-1 (ICAM-1), into the circulation.
Localization (release) of L-selectin associated with angina, coronary artery disease, ischemia and adhesions
1) Confidence 0.08 Published 1998 Journal Heart Vessels Section Abstract Doc Link 10442400 Disease Relevance 1.49 Pain Relevance 0.57
Increased release of the soluble form of the adhesion molecules L-selectin and ICAM-1 but not E-selectin during attacks of angina pectoris.
Localization (release) of L-selectin associated with angina and adhesions
2) Confidence 0.08 Published 1998 Journal Heart Vessels Section Title Doc Link 10442400 Disease Relevance 1.29 Pain Relevance 0.49
Upregulation of P-selectin and PECAM-1 and the co-localization of L-selectin and beta-endorphin in immunocytes suggest an important role of these adhesion molecules for the recruitment of immunocytes containing beta-endorphin to sites of painful inflammation.
Localization (co-localization) of L-selectin associated with pain, inflammation and adhesions
3) Confidence 0.07 Published 2000 Journal J. Neuroimmunol. Section Abstract Doc Link 10900350 Disease Relevance 0.66 Pain Relevance 0.47

General Comments

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