INT83468

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Context Info
Confidence 0.66
First Reported 1999
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 22
Total Number 22
Disease Relevance 2.91
Pain Relevance 2.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ELK3) mitochondrion (ELK3) nucleolus (ELK3)
nucleus (ELK3)
Anatomy Link Frequency
face 6
neurons 1
superior 1
brain 1
neural 1
ELK3 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 17 99.92 Very High Very High Very High
Pain 37 99.36 Very High Very High Very High
amygdala 612 97.80 Very High Very High Very High
insula 51 86.40 High High
tolerance 23 83.16 Quite High
Anterior cingulate 119 79.60 Quite High
Somatosensory cortex 51 78.80 Quite High
midbrain 2 51.96 Quite High
deep brain stimulation 1 47.12 Quite Low
positron emission tomography 6 34.40 Quite Low
Disease Link Frequency Relevance Heat
Sprains And Strains 48 99.60 Very High Very High Very High
Persistent Vegetative State 135 98.00 Very High Very High Very High
Anxiety Disorder 206 93.84 High High
Coma 14 77.12 Quite High
Pain 34 75.00 Quite High
Cognitive Disorder 89 67.16 Quite High
Mucocutaneous Lymph Node Syndrome 17 63.40 Quite High
Chronic Disease 6 62.20 Quite High
Diabetes Complications 14 60.92 Quite High
Diabetes Mellitus 138 59.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The strong dependence of ERP emotional expression effects on spatial attention demonstrated in our studies implies that the processes responsible for the generation of these effects are functionally distinct from this pre-attentive detection network.
Gene_expression (expression) of ERP associated with addiction
1) Confidence 0.66 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0 Pain Relevance 0.20
First, we found that ERP emotional expression effects were triggered at comparable latencies, and showed similar amplitudes and scalp topographies for all six basic emotions (Eimer et al., 2003).
Gene_expression (expression) of ERP
2) Confidence 0.66 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.06 Pain Relevance 0.19
From the distribution of this ERP, the task most likely involves bilateral activation of the superior parietal cortices.
Gene_expression (distribution) of ERP in superior
3) Confidence 0.59 Published 1999 Journal Exp Brain Res Section Abstract Doc Link 10442404 Disease Relevance 0.07 Pain Relevance 0.17
The observation that both short-latency as well as sustained longer latency ERP emotional expression effects are completely eliminated when emotional faces are presented at lateral positions and outside of the current focus of attention is clearly at odds with the hypothesis that emotional facial expression is always fully processed, regardless of other current task demands.
Gene_expression (expression) of ERP in faces
4) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0 Pain Relevance 0.03
If this was the case, one might have expected systematic differences between ERP emotional expression effects elicited by different facial expressions.
Gene_expression (expression) of ERP
5) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0 Pain Relevance 0.09
Thus, it is possible that some of these effects occur substantially later than the early ERP modulations found in our studies.
Gene_expression (modulations) of ERP
6) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.16 Pain Relevance 0.12
One obvious objection against this hypothesis is that it is highly unlikely that the effects of emotional expression on ERP waveforms reviewed in this paper are generated in the amygdala, given its deep position and its electrically closed nuclear structure of clustered neurons (unlike the regular alignment of neurons in layers of the neocortex).
Gene_expression (expression) of ERP in neurons associated with amygdala
7) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0 Pain Relevance 0.17
This was tested in another ERP study (Holmes, Kiss, & Eimer, 2006), where single faces (either fearful or neutral) were presented foveally at fixation, and were flanked by a pair of vertical lines that were either identical or different in length (see Fig. 7, top).
Gene_expression (presented) of ERP in faces
8) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0 Pain Relevance 0
Further studies will have to investigate to what extent effects of emotional facial expression on ERP waveforms, such as reviewed here, might represent the initial stages of higher level emotional processes, which may not just be involved in the analysis of emotionally relevant sensory stimuli, but perhaps also in the representation of subjective emotional states.



Gene_expression (expression) of ERP
9) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.06 Pain Relevance 0.18
ERP correlates of emotional face processing: other emotional expressions
Gene_expression (expressions) of ERP in face
10) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.21 Pain Relevance 0.10
While similar broadly distributed longer latency positivities have been reported in previous ERP studies for emotionally salient non-face stimuli (Cuthbert et al., 2000; Diedrich et al., 1997; Keil et al., 2002), differential ERP modulations at latencies below 200 ms have not been found with other types of emotional material, thus suggesting that such rapid effects might be specific for emotional faces (see Ashley et al., 2003, for similar early ERP effects of emotional facial expression).
Gene_expression (expression) of ERP in face
11) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.12 Pain Relevance 0.07
It appears much more plausible to assume that the impact of face inversion on the latency and amplitude of ERP emotional expression effects directly reflects the impairment of emotion detection and recognition produced by face inversion.
Gene_expression (expression) of ERP in face
12) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.06 Pain Relevance 0
The most important evidence against the hypothesis that ERP modulations sensitive to emotional facial expression are generated during the initial automatic classification of emotional content comes from our finding that spatial attention had a strong modulatory effect on these modulations.
Gene_expression (expression) of ERP
13) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.08 Pain Relevance 0.16
It has to be acknowledged that these tentative interpretations are primarily based on the results of a single ERP study, where systematic differences in ERP responses to specific facial expressions were conspicuously absent (Eimer, Holmes, & McGlone, 2003).
Gene_expression (expressions) of ERP
14) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.15 Pain Relevance 0.04
The similarity in the onset latencies of ERP emotional expression effects for all six basic emotional expressions suggests that emotionally relevant information delivered by facial expression is available to neocortical processes within less then 200 ms after stimulus onset, and at approximately the same time for all basic emotional expressions.
Gene_expression (expression) of ERP
15) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0 Pain Relevance 0
If the detection and analysis of different facial emotional expressions was mediated by distinct brain processes, this might also be reflected in systematic differences in the modulatory effects of these expressions on ERP waveforms.
Gene_expression (expressions) of ERP in brain
16) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0.23 Pain Relevance 0.12
It is conceivable that the early emotional expression effects observed in our ERP studies reflect activity within a neural network involved in the rapid automatic classification of emotional faces, which includes limbic structures as well as interconnected neocortical regions.
Gene_expression (expression) of ERP in neural
17) Confidence 0.58 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0 Pain Relevance 0.17
If LSF cues were more important than HSF cues in producing ERP modulations to fearful facial expressions, one would have expected to find stronger emotional expression effects for LSF as compared to HSF faces, with effects for LSF faces possibly even similar in magnitude to expression effects observed for unfiltered BSF faces.
Gene_expression (producing) of ERP in faces
18) Confidence 0.52 Published 2007 Journal Neuropsychologia Section Body Doc Link PMC2383989 Disease Relevance 0 Pain Relevance 0.03
The Australian Bureau of Statistics (ABS) does not produce a separate ERP figure for the Indigenous population in private dwellings, so the only other option using ABS data is to use census counts of people in private dwellings as the basis of comparison.
Neg (not) Gene_expression (produce) of ERP
19) Confidence 0.38 Published 2006 Journal BMC Public Health Section Body Doc Link PMC1373687 Disease Relevance 0.18 Pain Relevance 0
However, unlike the ERP figures, these counts do not take into account people who were not included in the Census or who did not respond to the question on Indigenous status, and the figures are only available for years in which a census was conducted.
Gene_expression (figures) of ERP
20) Confidence 0.33 Published 2006 Journal BMC Public Health Section Body Doc Link PMC1373687 Disease Relevance 0.16 Pain Relevance 0

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