INT83526

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Context Info
Confidence 0.41
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (Pnmt) cytoplasm (Pnmt)
Pnmt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 2 99.68 Very High Very High Very High
Catecholamine 2 94.24 High High
medulla 2 86.68 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glucocorticoids decrease phenylethanolamine N-methyltransferase mRNA expression in the immature foetal sheep adrenal.
Negative_regulation (decrease) of Gene_expression (expression) of phenylethanolamine N-methyltransferase associated with enkephalin
1) Confidence 0.41 Published 1999 Journal J. Neuroendocrinol. Section Title Doc Link 10444314 Disease Relevance 0 Pain Relevance 0.18
We conclude that before birth, adrenaline synthesis may be suppressed by a novel direct, or indirect, inhibitory effect of glucocorticoids on PNMT mRNA expression.
Negative_regulation (effect) of Gene_expression (expression) of PNMT mRNA
2) Confidence 0.41 Published 1999 Journal J. Neuroendocrinol. Section Abstract Doc Link 10444314 Disease Relevance 0 Pain Relevance 0.07

General Comments

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