INT8356

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Context Info
Confidence 0.32
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.43

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cell differentiation (YY1) intracellular (YY1) DNA binding (YY1)
extracellular space (Smpd1) chromosome organization (YY1) hydrolase activity, acting on glycosyl bonds (Smpd1)
YY1 (Homo sapiens)
Smpd1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 2 94.48 High High
agonist 1 85.84 High High
Opioid 4 83.28 Quite High
Enkephalin 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas ASM-5-67 bound to mu, delta, and kappa receptors with comparable affinities, ASM-5-10 was mu-selective, with selectivity indices (ratio of respective IC50 values) of 0.04 for both mu/delta and mu/kappa.
delta Binding (bound) of ASM-5-10
1) Confidence 0.32 Published 1992 Journal Biochem. Pharmacol. Section Abstract Doc Link 1371213 Disease Relevance 0 Pain Relevance 0.43

General Comments

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