INT83581

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Context Info
Confidence 0.49
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.07
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Brain 2
ras (Mus musculus)
Pain Link Frequency Relevance Heat
analgesia 5 100.00 Very High Very High Very High
beta blocker 5 79.64 Quite High
Intracerebroventricular 1 70.88 Quite High
tail-flick 1 66.84 Quite High
antagonist 21 54.08 Quite High
narcan 2 52.84 Quite High
opiate 1 52.32 Quite High
Nicotine 9 5.00 Very Low Very Low Very Low
Inflammation 7 5.00 Very Low Very Low Very Low
headache 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Canker Sores 68 100.00 Very High Very High Very High
Stress 17 100.00 Very High Very High Very High
Nicotine Addiction 76 98.84 Very High Very High Very High
Hypertension 95 97.52 Very High Very High Very High
Cough 4 90.32 High High
Ulcers 3 63.12 Quite High
Recurrence 2 57.76 Quite High
Disease 3 37.24 Quite Low
Renal Disease 7 30.52 Quite Low
Diabetes Mellitus 19 29.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When both these two factors; intensity and duration of cigarette smoking, were combined, even moderate cigarette smokers for periods more than five years and heavy cigarette smokers for periods less than five years had significantly lower risk of getting RAS (?
Positive_regulation (risk) of Localization (getting) of RAS associated with nicotine addiction and canker sores
1) Confidence 0.49 Published 2010 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2999509 Disease Relevance 1.86 Pain Relevance 0
Brain renin angiotensin system (RAS) in stress-induced analgesia and impaired retention.
Positive_regulation (stress-induced) of Localization (retention) of RAS in Brain associated with stress and analgesia
2) Confidence 0.14 Published 1999 Journal Peptides Section Title Doc Link 10447091 Disease Relevance 0.65 Pain Relevance 0.48
Combining an ACE inhibitor with an ARB could be used to prolong and increase RAS blockade.
Positive_regulation (increase) of Localization (blockade) of RAS
3) Confidence 0.04 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994016 Disease Relevance 0.22 Pain Relevance 0
Volume contraction is a stimulus for renin release and elevation of background RAS activity.
Positive_regulation (elevation) of Localization (release) of RAS
4) Confidence 0.03 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2663442 Disease Relevance 0.17 Pain Relevance 0.04
Volume contraction is a stimulus for renin release and elevation of background RAS activity.
Positive_regulation (stimulus) of Localization (release) of RAS
5) Confidence 0.03 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2663442 Disease Relevance 0.17 Pain Relevance 0.04

General Comments

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