INT83606

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Context Info
Confidence 0.43
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Scn10a) plasma membrane (Scn10a) transmembrane transport (Scn10a)
Scn10a (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 4 99.46 Very High Very High Very High
analgesia 2 99.00 Very High Very High Very High
Hyperalgesia 1 97.08 Very High Very High Very High
Inflammation 1 96.56 Very High Very High Very High
tetrodotoxin 8 88.28 High High
c fibre 1 84.12 Quite High
sodium channel 3 75.00 Quite High
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 3 99.46 Very High Very High Very High
Hyperalgesia 1 97.08 Very High Very High Very High
INFLAMMATION 1 96.56 Very High Very High Very High
Nociception 1 69.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data show that SNS is involved in pain pathways and suggest that blockade of SNS expression or function may produce analgesia without side effects.
Negative_regulation (blockade) of Gene_expression (expression) of SNS associated with pain and analgesia
1) Confidence 0.43 Published 1999 Journal Nat. Neurosci. Section Abstract Doc Link 10448219 Disease Relevance 0.51 Pain Relevance 1.36

General Comments

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