INT83624

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Context Info
Confidence 0.49
First Reported 1999
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.41
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cd59) plasma membrane (Cd59)
Anatomy Link Frequency
leukocytes 1
Cd59 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuritis 6 96.48 Very High Very High Very High
Demyelination 3 93.00 High High
cytokine 5 92.88 High High
Inflammation 10 88.48 High High
Kinase C 4 84.04 Quite High
Spinal cord 57 50.00 Quite Low
Central nervous system 29 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 6 96.48 Very High Very High Very High
Demyelinating Disease 3 93.00 High High
Cancer 3 91.04 High High
INFLAMMATION 10 88.48 High High
Necrosis 2 83.12 Quite High
Lifespan 1 80.84 Quite High
Syndrome 1 80.68 Quite High
Injury 57 67.92 Quite High
Spinal Cord Injury 70 5.00 Very Low Very Low Very Low
Central Nervous System Disease 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mac-1 (CD11b) positive leukocytes were localized close to the Schwann cells showing enhanced CD59 staining.
Positive_regulation (enhanced) of CD59 in leukocytes
1) Confidence 0.49 Published 1999 Journal J. Neurol. Sci. Section Abstract Doc Link 10450801 Disease Relevance 1.08 Pain Relevance 0.71
Furthermore, PMN expression of mRNAs encoding for these complement inhibitors in several other states of activity affirms the detection of membrane-bound CD59 and Crry proteins on PMN surfaces as demonstrated in previous studies [32,33], supporting a self-protective role for these PMN-generated inhibitors of complement-mediated lysis under certain stimulating conditions.
Positive_regulation (bound) of CD59
2) Confidence 0.28 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2443364 Disease Relevance 0.33 Pain Relevance 0.11

General Comments

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