INT83625

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Context Info
Confidence 0.15
First Reported 1999
Last Reported 1999
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tnf, Cd59) plasma membrane (Tnf, Cd59) signal transduction (Tnf)
extracellular region (Tnf) intracellular (Tnf) extracellular matrix organization (Tnf)
Anatomy Link Frequency
Schwann cells 2
Tnf (Rattus norvegicus)
Cd59 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 2 96.92 Very High Very High Very High
cytokine 1 94.60 High High
Neuritis 6 94.40 High High
Demyelination 2 83.16 Quite High
Disease Link Frequency Relevance Heat
Necrosis 1 99.72 Very High Very High Very High
Cancer 1 99.54 Very High Very High Very High
INFLAMMATION 2 96.92 Very High Very High Very High
Experimental Autoimmune Neuritis 6 94.40 High High
Demyelinating Disease 2 83.16 Quite High
Syndrome 1 70.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, interferon gamma (IFN-gamma) or tumor necrosis factor alfa (TNF-alpha) did not upregulate the expression of CD59 on rat Schwann cells in culture.
TNF-alpha Neg (not) Positive_regulation (upregulate) of Gene_expression (expression) of CD59 in Schwann cells associated with necrosis and cancer
1) Confidence 0.15 Published 1999 Journal J. Neurol. Sci. Section Abstract Doc Link 10450801 Disease Relevance 1.08 Pain Relevance 0.69

General Comments

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