INT8363

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.81
First Reported 1980
Last Reported 2010
Negated 0
Speculated 6
Reported most in Abstract
Documents 135
Total Number 141
Disease Relevance 14.29
Pain Relevance 61.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nts)
Anatomy Link Frequency
brain 8
ileum 6
spinal cord 5
PAG 4
nucleus 4
Nts (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 1544 100.00 Very High Very High Very High
medulla 351 100.00 Very High Very High Very High
gABA 181 100.00 Very High Very High Very High
Enkephalin 160 100.00 Very High Very High Very High
Neuropeptide 113 100.00 Very High Very High Very High
substance P 102 100.00 Very High Very High Very High
Dopamine 99 100.00 Very High Very High Very High
Somatostatin 67 100.00 Very High Very High Very High
Spinal cord 54 100.00 Very High Very High Very High
Opioid 37 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
INFLAMMATION 60 100.00 Very High Very High Very High
Paralysis 2 99.74 Very High Very High Very High
Apnoea 162 99.68 Very High Very High Very High
Urological Neuroanatomy 98 99.68 Very High Very High Very High
Increased Venous Pressure Under Development 4 99.54 Very High Very High Very High
Heart Rate Under Development 3 98.92 Very High Very High Very High
Nociception 66 98.40 Very High Very High Very High
Pressure Volume 2 Under Development 3 98.28 Very High Very High Very High
Pain 67 98.24 Very High Very High Very High
Schizophrenia 6 97.56 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results suggest that the release of neurotensin is influenced by nervous pathways involving nicotinic and opioid receptors.
Localization (release) of neurotensin associated with opioid receptor
1) Confidence 0.81 Published 1984 Journal Acta Physiol. Scand. Section Abstract Doc Link 6095596 Disease Relevance 0 Pain Relevance 0.45
The existence of possible local mediators of the inhibitory effect of neurotensin on gastric acid secretion has not been determined.
Localization (secretion) of neurotensin
2) Confidence 0.81 Published 1991 Journal Life Sci. Section Abstract Doc Link 1671292 Disease Relevance 0 Pain Relevance 0.30
As direct and indirect dopamine agonists have been reported to promote neurotensin release in the cortex, behavioural studies were performed using injection of apomorphine.
Localization (release) of neurotensin in cortex associated with dopamine and agonist
3) Confidence 0.80 Published 1995 Journal Fundam Clin Pharmacol Section Abstract Doc Link 8808171 Disease Relevance 0.25 Pain Relevance 0.66
The distributions of neurotensin and opiate receptors within the dorsal horn of the rat spinal cord were studied with quantitative autoradiographic techniques and compared with the immunohistochemical localizations of neurotensin and methionine-enkephalin-like immunoreactivity in this region.
Localization (localizations) of neurotensin in spinal cord associated with dorsal horn, enkephalin, opiate and spinal cord
4) Confidence 0.80 Published 1981 Journal Brain Res. Section Abstract Doc Link 6172180 Disease Relevance 0 Pain Relevance 0.80
Ultrastructural localization of immunoreactive neurotensin in the monkey superficial dorsal horn.
Localization (localization) of neurotensin in dorsal horn associated with neuropeptide and dorsal horn
5) Confidence 0.79 Published 1984 Journal J. Comp. Neurol. Section Title Doc Link 6373845 Disease Relevance 0.09 Pain Relevance 0.28
The light microscopic and ultrastructural localization of neurotensin immunoreactivity in neurons of the monkey spinal cord was studied with the aim of examining their synaptic interactions.
Localization (localization) of neurotensin in spinal cord associated with spinal cord
6) Confidence 0.79 Published 1984 Journal J. Comp. Neurol. Section Abstract Doc Link 6373845 Disease Relevance 0.10 Pain Relevance 0.22
The decrease of the immunoreactivity in the ipsilateral side (stimulated) suggests that methionine enkephalin, neurotensin and somatostatin 28 are released in the caudal trigeminal nucleus after electrical stimulation of the trigeminal ganglion; 2.
Localization (released) of neurotensin in nucleus
7) Confidence 0.79 Published 2002 Journal Rev Neurol Section Body Doc Link 12080490 Disease Relevance 0.16 Pain Relevance 0
Neurotensin receptor localization by light microscopic autoradiography in rat brain.
Localization (localization) of Neurotensin in brain
8) Confidence 0.78 Published 1981 Journal Brain Res. Section Title Doc Link 6260280 Disease Relevance 0 Pain Relevance 0.12
The light microscopic localization of the neurotensin receptor has been carried out by the autoradiographic localization of [3H]neurotensin binding sites in slide-mounted tissue sections.
Localization (localization) of neurotensin
9) Confidence 0.78 Published 1981 Journal Brain Res. Section Abstract Doc Link 6260280 Disease Relevance 0 Pain Relevance 0.11
Luminal bile salts and neurotensin release in the isolated vascularly perfused rat jejuno-ileum.
Localization (release) of neurotensin in ileum associated with bile
10) Confidence 0.78 Published 1994 Journal Endocrinology Section Title Doc Link 8299558 Disease Relevance 0 Pain Relevance 0.30
Bile salts in the distal small intestine are strong stimulants of neurotensin (NT) release, but the underlying mechanisms are not known.
Localization (release) of neurotensin in small intestine associated with bile
11) Confidence 0.78 Published 1994 Journal Endocrinology Section Abstract Doc Link 8299558 Disease Relevance 0 Pain Relevance 0.27
It is possible that neurotensin released from these cells in the mucosa as well as neurotensin-related peptides released from enteric neurons may be the endogenous ligands for the binding sites visualized in this study.
Localization (released) of neurotensin in neurons
12) Confidence 0.78 Published 1990 Journal Synapse Section Abstract Doc Link 2169072 Disease Relevance 0 Pain Relevance 0.09
Immunohistochemical localization of neurotensin in the porcine jejunum demonstrated a limited population of neurotensin immunoreactive cells within the mucosal epithelium.
Localization (localization) of neurotensin in epithelium
13) Confidence 0.78 Published 1990 Journal Synapse Section Abstract Doc Link 2169072 Disease Relevance 0 Pain Relevance 0.10
Patterns of co-localization of serotonin with glutamate decarboxylase (the synthetic enzyme for GABA) or each one of eight neuropeptides (calcitonin gene-related peptide, dynorphin, enkephalin, galanin, neuropeptide Y, neurotensin, substance P and somatostatin) were investigated with dual-colour confocal laser scanning microscopy in the lumbar spinal cords of three adult rats.
Spec (investigated) Localization (co-localization) of neurotensin in spinal cords associated with somatostatin, enkephalin, calcitonin gene-related peptide, glutamate, gaba, dynorphin, neuropeptide, serotonin and substance p
14) Confidence 0.78 Published 1996 Journal Neuroscience Section Abstract Doc Link 8931011 Disease Relevance 0 Pain Relevance 0.79
Localization of neurotensin NTS2 receptors in rat brain, using.
Localization (Localization) of neurotensin in brain
15) Confidence 0.78 Published 2001 Journal Neuroreport Section Title Doc Link 11303751 Disease Relevance 0.08 Pain Relevance 0.40
Release of neurotensin from rat spinal cord in vitro.
Localization (Release) of neurotensin in spinal cord associated with spinal cord
16) Confidence 0.77 Published 1983 Journal Neurosci. Lett. Section Title Doc Link 6134263 Disease Relevance 0 Pain Relevance 0.33
We found that D2 agonist-elicited increases in PFC GABA levels were blocked by pretreatment with SR48692, consistent with data indicating that D2 autoreceptor agonists increase neurotensin release from dopamine-neurotensin axons in the PFC.
Localization (release) of neurotensin in PFC associated with dopamine, gaba and agonist
17) Confidence 0.77 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 15716398 Disease Relevance 0.05 Pain Relevance 0.70
These results strongly suggest the presence of two subsets of neurotensin receptors in the ileum: the inhibitory set probably localized at the postsynaptic effector level and excitatory neurotensin receptors probably of neuronal origin whose function is probably to modulate the release of neurotransmitters.
Localization (localized) of neurotensin in ileum associated with neurotransmitter
18) Confidence 0.77 Published 1984 Journal Eur. J. Pharmacol. Section Abstract Doc Link 6090161 Disease Relevance 0 Pain Relevance 0.32
Neurotensin potentiates the potassium-induced release of endogenous dopamine from rat striatal slices.
Localization (release) of Neurotensin associated with dopamine
19) Confidence 0.75 Published 1983 Journal Eur. J. Pharmacol. Section Title Doc Link 6628546 Disease Relevance 0 Pain Relevance 0.52
The effects of neurotensin on the release of endogenous dopamine (DA) from rat striatal slices were investigated.
Localization (release) of neurotensin associated with dopamine
20) Confidence 0.75 Published 1983 Journal Eur. J. Pharmacol. Section Abstract Doc Link 6628546 Disease Relevance 0 Pain Relevance 0.35

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox