INT83678

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Context Info
Confidence 0.17
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.14
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCB4) small molecule metabolic process (ABCB4) ATPase activity (ABCB4)
plasma membrane (ABCB4) transmembrane transport (ABCB4) lipid metabolic process (ABCB4)
ABCB4 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 4 99.02 Very High Very High Very High
Analgesic 6 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 2 68.40 Quite High
Disease 3 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Pancytopenia 1 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Sunburn 1 5.00 Very Low Very Low Very Low
Chronic Disease 1 5.00 Very Low Very Low Very Low
Rheumatic Diseases 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface.
resistance P-glycoprotein Binding (binding) of associated with qutenza
1) Confidence 0.17 Published 1999 Journal J. Biol. Chem. Section Title Doc Link 10455147 Disease Relevance 0 Pain Relevance 0.17
The human multidrug resistance P-glycoprotein (P-gp) is organized in two tandem repeats with each repeat consisting of an N-terminal hydrophobic domain containing six potential transmembrane segments followed by a hydrophilic domain containing a nucleotide-binding fold.
resistance P-glycoprotein Binding (organized) of
2) Confidence 0.17 Published 1999 Journal J. Biol. Chem. Section Abstract Doc Link 10455147 Disease Relevance 0 Pain Relevance 0
In the inference process for these predictions, we used all the known drugs and target proteins in the gold standard data as training data, and predicted potential interactions for all compounds in KEGG LIGAND and all the other drugs in KEGG DRUG (the drugs are absent from the gold standard data).
KEGG DRUG Binding (interactions) of
3) Confidence 0.01 Published 2010 Journal Bioinformatics Section Body Doc Link PMC2881361 Disease Relevance 0.14 Pain Relevance 0

General Comments

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