INT83681

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Context Info
Confidence 0.49
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.06
Pain Relevance 2.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (CA3) cytoplasm (CA3)
Anatomy Link Frequency
dentate gyrus 1
hippocampus 1
CA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
long-term potentiation 38 100.00 Very High Very High Very High
Opioid 7 99.70 Very High Very High Very High
narcan 4 99.64 Very High Very High Very High
Enkephalin 1 99.40 Very High Very High Very High
antagonist 3 99.12 Very High Very High Very High
Hippocampus 2 99.08 Very High Very High Very High
opioid receptor 3 98.52 Very High Very High Very High
Delta opioid receptors 1 94.60 High High
Morphine 7 88.00 High High
MU agonist 2 59.76 Quite High
Disease Link Frequency Relevance Heat
Aging 1 60.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The lateral aspect of the perforant path contains and releases enkephalin-derived opioid peptides, and induction of long-term potentiation (LTP) in lateral perforant path projections to both the dentate gyrus and the hippocampal CA3 region is blocked by antagonists of opioid receptors.
Positive_regulation (induction) of CA3 in dentate gyrus associated with antagonist, opioid receptor, long-term potentiation, enkephalin and opioid
1) Confidence 0.49 Published 2008 Journal J. Neurophysiol. Section Abstract Doc Link 18199817 Disease Relevance 0.06 Pain Relevance 1.11
Properties of LTP induction in the CA3 region of the primate hippocampus.
Positive_regulation (induction) of CA3 in hippocampus associated with narcan and hippocampus
2) Confidence 0.12 Published 1996 Journal Learn. Mem. Section Title Doc Link 10456079 Disease Relevance 0 Pain Relevance 0.75
We have begun to test this hypothesis by studying the properties and mechanisms of LTP induction in area CA3 of hippocampal slices from cynomolgus monkeys.
Positive_regulation (induction) of CA3 associated with long-term potentiation
3) Confidence 0.11 Published 1996 Journal Learn. Mem. Section Abstract Doc Link 10456079 Disease Relevance 0 Pain Relevance 0.74

General Comments

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