INT83733

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Context Info
Confidence 0.24
First Reported 1999
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 12
Total Number 12
Disease Relevance 4.32
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein folding (TUBB3) structural molecule activity (TUBB3) cytoskeleton (TUBB3)
GTPase activity (TUBB3) cytoplasm (TUBB3)
Anatomy Link Frequency
nurse cells 3
neurons 2
astrocytes 1
SHED 1
stem cells 1
TUBB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 21 95.60 Very High Very High Very High
Central nervous system 26 93.16 High High
tetrodotoxin 3 55.36 Quite High
Neuropeptide 5 25.00 Low Low
Nerve growth factor 5 25.00 Low Low
Somatostatin 3 25.00 Low Low
enkephalin 3 25.00 Low Low
cva 50 5.00 Very Low Very Low Very Low
Spinal cord 33 5.00 Very Low Very Low Very Low
Glutamate 20 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Generalized Anxiety Disorder 3 99.92 Very High Very High Very High
Rheumatoid Arthritis 14 99.52 Very High Very High Very High
Obesity 7 96.64 Very High Very High Very High
Weight Loss 6 96.48 Very High Very High Very High
Nicotine Addiction 63 95.76 Very High Very High Very High
Disease 33 94.36 High High
Non-small-cell Lung Cancer 26 93.68 High High
Toxicity 8 92.40 High High
Neuroblastoma 3 90.12 High High
Systemic Lupus Erythematosus 64 78.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A1 hybrid neurons express neuron-specific markers such as neurofilament-L (NF-L), NF-M, NF-H, MAP-2, and beta tubulin III.
Gene_expression (express) of beta tubulin III in neuron
1) Confidence 0.24 Published 2002 Journal Neurobiol. Dis. Section Abstract Doc Link 12460557 Disease Relevance 0.32 Pain Relevance 0.15
In contrast to the medullary RE cells, these subcapsular nurse cells also produce thymosins beta 3 and beta 4.
Gene_expression (produce) of thymosins beta 3 and beta 4 in nurse cells
2) Confidence 0.15 Published 2000 Journal Anticancer Res. Section Abstract Doc Link 10928121 Disease Relevance 0 Pain Relevance 0
In contrast to the medullary RE cells, these subcapsular nurse cells also produce thymosins beta 3 and beta 4.
Gene_expression (produce) of thymosins beta 3 and beta 4 in nurse cells
3) Confidence 0.13 Published 2000 Journal Anticancer Res. Section Abstract Doc Link 10928121 Disease Relevance 0 Pain Relevance 0
-tubulin III, a neurons specific marker and GFAP, a marker for astrocytes, were expressed prior to undergoing differentiation [7].
Gene_expression (expressed) of tubulin III in astrocytes
4) Confidence 0.12 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2092394 Disease Relevance 0.11 Pain Relevance 0
In contrast to medullar RE cells, these subcapsular nurse cells also produce thymosins beta 3 beta 4.
Gene_expression (produce) of thymosins beta 3 beta 4 in nurse cells
5) Confidence 0.11 Published 1999 Journal In Vivo Section Abstract Doc Link 10459506 Disease Relevance 0 Pain Relevance 0
Additionally, molecular markers such as p53 and ras mutations, and expression of ERCC1, beta-tubulin III and RRM1, have been found to influence treatment outcome 5,13-15.
Gene_expression (expression) of beta-tubulin III
6) Confidence 0.10 Published 2011 Journal Journal of Cancer Section Body Doc Link PMC3020361 Disease Relevance 1.87 Pain Relevance 0
-tubulin III neurons, suggesting nearly as many hCNS-SCns differentiated into neurons as oligodendrocytes (Fig. 5).
Gene_expression (neurons) of tubulin III in oligodendrocytes
7) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923623 Disease Relevance 0 Pain Relevance 0
-tubulin III neurons suggesting hCNS-SCns differentiated into neurons (Fig. 4K–O).
Gene_expression (neurons) of tubulin III in neurons
8) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923623 Disease Relevance 0.05 Pain Relevance 0
tubulin III was expressed in fewer cells (2.1-2.8%).
Gene_expression (expressed) of tubulin III
9) Confidence 0.01 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2826742 Disease Relevance 0.27 Pain Relevance 0.06
tubulin III, GFAP and GalC per total B2A1 cells following incubation in DM4 serum-free medium, treated with serum or various growth factors, are presented in Table 3.
Gene_expression (presented) of tubulin III
10) Confidence 0.01 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2826742 Disease Relevance 0.15 Pain Relevance 0.09
As neural crest cell-associated postnatal stem cells, SHED express a variety of neural cell markers including nestin, beta III tubulin, GAD, NeuN, GFAP, NFM, and CNPase [21].
Gene_expression (express) of III tubulin in stem cells associated with generalized anxiety disorder
11) Confidence 0.01 Published 2010 Journal Stem Cell Res Ther Section Body Doc Link PMC2873699 Disease Relevance 0.77 Pain Relevance 0
As neural crest cell-associated postnatal stem cells, SHED express a variety of neural cell markers including nestin, beta III tubulin, GAD, NeuN, GFAP, NFM, and CNPase [21].
Gene_expression (express) of III tubulin in SHED associated with generalized anxiety disorder
12) Confidence 0.00 Published 2010 Journal Stem Cell Res Ther Section Body Doc Link PMC2873699 Disease Relevance 0.77 Pain Relevance 0

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