INT83749

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Context Info
Confidence 0.21
First Reported 1999
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.14
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) nucleolus (Fos) nucleus (Fos)
plasma membrane (Gnrhr) DNA binding (Fos) transcription factor binding (Fos)
Anatomy Link Frequency
neurons 2
Gnrhr (Rattus norvegicus)
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Versed 2 99.68 Very High Very High Very High
Hippocampus 2 91.72 High High
depression 1 89.88 High High
long-term potentiation 7 88.88 High High
Morphine 4 75.00 Quite High
gABA 3 53.16 Quite High
Glutamate receptor 1 51.96 Quite High
anesthesia 5 5.00 Very Low Very Low Very Low
addiction 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 1 89.88 High High
Apoptosis 1 54.52 Quite High
Amnesia 4 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Aids-related Complex 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Growth hormone secretagogues (GHS) administered systemically selectively induce growth hormone (GH) release from the pituitary and the expression of Fos protein in arcuate nucleus neurons.
Growth hormone Positive_regulation (induce) of Gene_expression (expression) of Fos in neurons
1) Confidence 0.21 Published 1999 Journal Neuroendocrinology Section Abstract Doc Link 10461024 Disease Relevance 0 Pain Relevance 0.15
Previous reports suggest the involvement of the MAPK/ERK pathway in the induction of c-Fos and Egr-1 expression by growth hormone[25] or midazolam[12].
growth hormone Positive_regulation (induction) of Gene_expression (expression) of c-Fos associated with versed
2) Confidence 0.07 Published 2010 Journal BMC Res Notes Section Body Doc Link PMC2916009 Disease Relevance 0.14 Pain Relevance 0.24

General Comments

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