INT83805

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Context Info
Confidence 0.00
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.15
Pain Relevance 1.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EPHB3) plasma membrane (EPHB3)
Anatomy Link Frequency
DRG 1
EPHB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 10 99.58 Very High Very High Very High
antagonist 2 99.34 Very High Very High Very High
agonist 2 99.14 Very High Very High Very High
dorsal root ganglion 16 97.68 Very High Very High Very High
Root ganglion neuron 2 75.00 Quite High
nociceptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 18 97.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The competitive vanilloid receptor antagonist capsazepine inhibited [(3)H]RTX binding to HEK293/VR1 cells with a K(i) value of 6.2 microM and binding to DRG membranes with a K(i) value of 8.6 microM.
HEK293 Binding (binding) of in DRG associated with dorsal root ganglion and antagonist
1) Confidence 0.00 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 10462546 Disease Relevance 0.60 Pain Relevance 0.67
The typical vanilloid agonists olvanil and capsaicin inhibited [(3)H]RTX binding to HEK293/VR1 cells with K(i) values of 0.4 and 4.0 microM, respectively.
HEK293 Binding (binding) of associated with qutenza and agonist
2) Confidence 0.00 Published 1999 Journal Mol. Pharmacol. Section Abstract Doc Link 10462546 Disease Relevance 0.55 Pain Relevance 0.52

General Comments

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