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Context Info
Confidence 0.49
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Penk, Npff) extracellular space (Npff)
Anatomy Link Frequency
spinal 1
Penk (Rattus norvegicus)
Npff (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 3 100.00 Very High Very High Very High
Opioid 3 100.00 Very High Very High Very High
Antinociceptive 2 100.00 Very High Very High Very High
Kappa opioid receptor 1 93.92 High High
antagonist 1 84.08 Quite High
opioid receptor 1 83.64 Quite High
intrathecal 2 81.80 Quite High
Neuropeptide 2 75.00 Quite High
Spinal cord 1 75.00 Quite High
halothane 1 71.96 Quite High
Disease Link Frequency Relevance Heat
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data provide the first direct demonstration that met-enkephalin (among other opioid peptides) can mediate the antinociceptive action of NPFF at the spinal level in rats.
enkephalin Positive_regulation (mediate) of NPFF in spinal associated with enkephalin, antinociceptive and opioid
1) Confidence 0.49 Published 1999 Journal Neuropharmacology Section Abstract Doc Link 10471085 Disease Relevance 0 Pain Relevance 1.02

General Comments

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