INT83959

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Context Info
Confidence 0.33
First Reported 1999
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Npy) extracellular region (Npy)
Anatomy Link Frequency
neurons 2
Npy (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 2 98.08 Very High Very High Very High
guanethidine 1 97.40 Very High Very High Very High
gABA 6 97.36 Very High Very High Very High
Neuropeptide 5 90.16 High High
substance P 1 76.48 Quite High
Calcitonin gene-related peptide 1 75.44 Quite High
Enkephalin 1 72.80 Quite High
GABAergic 9 63.92 Quite High
Somatostatin 11 10.24 Low Low
Action potential 22 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 90.00 High High
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NPY neurons signal through a complex release of NPY, AgRP, and ?
Regulation (signal) of Localization (release) of NPY in neurons
1) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2820089 Disease Relevance 0.09 Pain Relevance 0.15
Pretreatment with prazosin or haloperidol affected neither the release of NPY nor the morphologic changes; pretreatment with tetrodotoxin and guanethidine abolished NPY release and prevented the PTX-B-induced morphologic changes.
Neg (neither) Regulation (affected) of Neg (neither) Localization (release) of NPY associated with tetrodotoxin and guanethidine
2) Confidence 0.27 Published 1999 Journal Peptides Section Abstract Doc Link 10477080 Disease Relevance 0 Pain Relevance 0.38

General Comments

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