INT84018

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Context Info
Confidence 0.65
First Reported 1999
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 15
Total Number 16
Disease Relevance 8.27
Pain Relevance 2.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (RNASE3)
Anatomy Link Frequency
eosinophil 8
nasal 3
stage 0 1
neutrophils 1
RNASE3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 100 100.00 Very High Very High Very High
Inflammatory marker 7 99.84 Very High Very High Very High
Inflammation 236 98.24 Very High Very High Very High
local anesthetic 4 95.12 Very High Very High Very High
chemokine 11 91.00 High High
dexamethasone 2 81.36 Quite High
metalloproteinase 1 80.92 Quite High
lidocaine 9 58.12 Quite High
aspirin 1 47.48 Quite Low
visual analogue scale 1 10.88 Low Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 81 100.00 Very High Very High Very High
Cancer 17 100.00 Very High Very High Very High
Necrosis 15 100.00 Very High Very High Very High
INFLAMMATION 241 99.84 Very High Very High Very High
Nasal Polyps 11 99.54 Very High Very High Very High
Mucositis 12 98.24 Very High Very High Very High
Hypersensitivity 66 92.20 High High
Chronic Sinusitis 7 91.52 High High
Disease 82 90.40 High High
Nicotine Addiction 162 87.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The analyses included myeloperoxidase (MPO), eosinophil cationic protein (ECP), lysozyme, and albumin and were carried out at the Department of Clinical Chemistry, University Hospital, Uppsala, Sweden.
Spec (analyses) Gene_expression (included) of eosinophil cationic protein in eosinophil associated with urological neuroanatomy
1) Confidence 0.65 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1314919 Disease Relevance 0.24 Pain Relevance 0.05
Mucosal inflammation symptoms correlated with increased levels of albumin, but not with increased levels of ECP, secreted proinflammatory cytokines or cytokine gene mRNA expression.
Gene_expression (expression) of ECP associated with mucositis, inflammation and cytokine
2) Confidence 0.52 Published 2001 Journal Acta Otolaryngol. Section Abstract Doc Link 11678174 Disease Relevance 0.54 Pain Relevance 0.46
Albumin and ECP, and the cytokines tumor necrosis factor-alpha (TNF-alpha) and interleukin-8 (IL-8), were used as inflammatory markers.
Gene_expression (used) of ECP associated with necrosis, cancer, inflammatory marker and cytokine
3) Confidence 0.45 Published 2001 Journal Acta Otolaryngol. Section Abstract Doc Link 11678174 Disease Relevance 0.64 Pain Relevance 0.46
Specific IgE, eosinophil cationic protein, eosinophil protein X, and tryptase levels were measured in each patient's serum.
Gene_expression (levels) of eosinophil cationic protein in eosinophil
4) Confidence 0.42 Published 1999 Journal J. Allergy Clin. Immunol. Section Body Doc Link 10482840 Disease Relevance 0.25 Pain Relevance 0
Furthermore, increased levels of eosinophil cationic protein (ECP) and albumin, but not tryptase, in nasal lavage from workers exposed to UV coatings have been observed.
Gene_expression (levels) of ECP in nasal
5) Confidence 0.35 Published 2001 Journal Acta Otolaryngol. Section Abstract Doc Link 11678174 Disease Relevance 0.21 Pain Relevance 0.13
Furthermore, increased levels of eosinophil cationic protein (ECP) and albumin, but not tryptase, in nasal lavage from workers exposed to UV coatings have been observed.
Gene_expression (levels) of eosinophil cationic protein in nasal
6) Confidence 0.35 Published 2001 Journal Acta Otolaryngol. Section Abstract Doc Link 11678174 Disease Relevance 0.20 Pain Relevance 0.13
ECP and MPO were also measured using commercially available assays (Phadia, Uppsala, Sweden and Calbiochem, Darmstadt, Germany, repectively).
Gene_expression (measured) of ECP associated with urological neuroanatomy
7) Confidence 0.12 Published 2008 Journal Respir Res Section Body Doc Link PMC2253533 Disease Relevance 0.19 Pain Relevance 0.06
Differences in nasal lavage fluid levels of MPO, ECP, IL-8, and ?
Gene_expression (levels) of ECP in nasal associated with urological neuroanatomy
8) Confidence 0.11 Published 2008 Journal Respir Res Section Body Doc Link PMC2253533 Disease Relevance 0.44 Pain Relevance 0
The sections were blinded and the numbers of ECP-positive (eosinophils) and MPO-positive (neutrophils) subepithelial cells were counted down to a depth of 210 ?
Gene_expression (positive) of ECP in neutrophils associated with urological neuroanatomy
9) Confidence 0.11 Published 2008 Journal Respir Res Section Body Doc Link PMC2253533 Disease Relevance 0.30 Pain Relevance 0
The monoclonal antibody EG2 (Phadia, dilution 1:200), which detects the eosinophil granule protein ECP, was used to identify eosinophils.
Gene_expression (detects) of ECP in eosinophils
10) Confidence 0.10 Published 2008 Journal Respir Res Section Body Doc Link PMC2253533 Disease Relevance 0.25 Pain Relevance 0
Lavage fluid levels of myeloperoxidase (MPO), eosinophil cationic protein (ECP), ?
Gene_expression (levels) of eosinophil cationic protein in eosinophil associated with urological neuroanatomy
11) Confidence 0.10 Published 2008 Journal Respir Res Section Body Doc Link PMC2253533 Disease Relevance 0.61 Pain Relevance 0.17
Lavage fluid levels of myeloperoxidase (MPO), eosinophil cationic protein (ECP), ?
Gene_expression (levels) of ECP in eosinophil associated with urological neuroanatomy
12) Confidence 0.10 Published 2008 Journal Respir Res Section Body Doc Link PMC2253533 Disease Relevance 0.61 Pain Relevance 0.17
After short term treatment with glucocorticoids a significant decrease in the levels of serum eosinophil cationic protein (ECP) and serum eosinophil peroxidase was observed [43].
Gene_expression (levels) of ECP in eosinophil
13) Confidence 0.05 Published 2004 Journal Clin Mol Allergy Section Body Doc Link PMC425596 Disease Relevance 0.46 Pain Relevance 0.09
After short term treatment with glucocorticoids a significant decrease in the levels of serum eosinophil cationic protein (ECP) and serum eosinophil peroxidase was observed [43].
Gene_expression (levels) of cationic protein in eosinophil
14) Confidence 0.05 Published 2004 Journal Clin Mol Allergy Section Body Doc Link PMC425596 Disease Relevance 0.46 Pain Relevance 0.09
GOLD stage III had higher levels of IL-8 than GOLD stage 0 (27.7 ng/ml and 8.7 ng/ml respectively) and lower ECP levels than GOLD stage II (87 ?
Gene_expression (levels) of ECP in stage 0
15) Confidence 0.05 Published 2005 Journal Respir Res Section Body Doc Link PMC1140754 Disease Relevance 1.52 Pain Relevance 0.04
A Th2 pattern predominates in nasal polyposis, characterized by IgE production, infiltration of eosinophils and upregulation of cytokines and mediators, including IL-5, ECP and eotaxin, that drive eosinophil response.59 Staphylococcus aureus enterotoxins may play a role in the pathophysiology of NP.
Gene_expression (production) of ECP in eosinophils associated with nasal polyps and cytokine
16) Confidence 0.01 Published 2010 Journal International Journal of General Medicine Section Body Doc Link PMC2866558 Disease Relevance 1.33 Pain Relevance 0.27

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