INT84019

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Context Info
Confidence 0.07
First Reported 1999
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.84
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (TPSD1) extracellular region (TPSD1)
Anatomy Link Frequency
eosinophil 1
mast cells 1
TPSD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
pruritus 1 76.56 Quite High
Pain 1 62.48 Quite High
Antihistamine 1 25.00 Low Low
cytokine 1 10.00 Low Low
chemokine 1 10.00 Low Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Mastocytosis 5 88.20 High High
Disease 3 83.84 Quite High
Gastroenteritis 1 82.00 Quite High
Hyperplasia 1 81.52 Quite High
Rhinitis 1 81.36 Quite High
Mastocytosis 5 78.60 Quite High
Cutaneous Mastocytosis 5 77.44 Quite High
Pruritus 1 76.56 Quite High
Increased Venous Pressure Under Development 1 75.76 Quite High
Urticaria 1 75.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Specific IgE, eosinophil cationic protein, eosinophil protein X, and tryptase levels were measured in each patient's serum.
Gene_expression (levels) of tryptase in eosinophil
1) Confidence 0.07 Published 1999 Journal J. Allergy Clin. Immunol. Section Body Doc Link 10482840 Disease Relevance 0.25 Pain Relevance 0
Four minor criteria include the presence of elevated serum alpha-tryptase levels > 20 ng/mL, the expression of CD2 and CD25 surface markers in c-kit-positive mast cells from bone marrow or other organs, the presence of a c-kit mutations on bone marrow and/or other tissues mast cells, and the presence of > 25% abnormal spindle-shaped mast cells in bone marrow and/or tissues.
Gene_expression (expression) of alpha-tryptase in mast cells
2) Confidence 0.00 Published 2004 Journal Allergy Asthma Proc Section Abstract Doc Link 15055560 Disease Relevance 1.59 Pain Relevance 0.10

General Comments

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