INT84038

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Context Info
Confidence 0.86
First Reported 1999
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.69
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn1) extracellular region (Edn1) cell-cell signaling (Edn1)
cytoplasm (Edn1)
Anatomy Link Frequency
plasma 1
Edn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 1 98.52 Very High Very High Very High
ischemia 2 90.64 High High
anesthesia 3 77.68 Quite High
antagonist 1 25.00 Low Low
medulla 19 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Natriuresis 1 99.44 Very High Very High Very High
Body Weight 7 97.12 Very High Very High Very High
Cv Unclassified Under Development 2 90.64 High High
Acute Renal Failure 6 89.28 High High
Diabetes Mellitus 132 50.00 Quite Low
Renal Disease 8 5.00 Very Low Very Low Very Low
Hyperglycemia 7 5.00 Very Low Very Low Very Low
Hypertrophy 5 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Body Weight Changes 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neutral endopeptidase (NEP, 24.11) is an ectoenzyme involved in the degradation of peptide hormones such as endothelin (ET), atrial natriuretic factor and enkephalins.
Protein_catabolism (degradation) of endothelin associated with natriuresis and enkephalin
1) Confidence 0.86 Published 1999 Journal Mol. Cell. Biochem. Section Abstract Doc Link 10485324 Disease Relevance 0.59 Pain Relevance 0.26
The concentration of ET-1 was determined in plasma.
Protein_catabolism (concentration) of ET-1 in plasma
2) Confidence 0.57 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC555576 Disease Relevance 0.10 Pain Relevance 0

General Comments

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