INT84079

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Context Info
Confidence 0.45
First Reported 1999
Last Reported 2000
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.18
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MDH2) small molecule metabolic process (MDH2) oxidoreductase activity (MDH2)
nucleolus (MDH2) plasma membrane (MDH2) nucleus (MDH2)
Anatomy Link Frequency
dorsal horn 1
parietal 1
MDH2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dorsal horn 7 100.00 Very High Very High Very High
unmyelinated 2 97.48 Very High Very High Very High
fifth nerve 1 94.28 High High
qutenza 4 89.76 High High
referred pain 1 89.28 High High
headache 1 87.76 High High
medulla 1 75.00 Quite High
nociceptor 2 58.72 Quite High
Neuronal excitability 1 44.48 Quite Low
cva 1 35.68 Quite Low
Disease Link Frequency Relevance Heat
Referred Pain 1 89.28 High High
Headache 1 87.76 High High
Cv General 3 Under Development 1 35.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The noxious stimulus-dependent induction of c-Fos-like immunoreactivity (Fos-LI) in neurons in the subnucleus oralis and the medullary dorsal horn (MDH) was significantly suppressed by the selective destruction of unmyelinated primary neurons.
Positive_regulation (induction) of MDH in dorsal horn associated with dorsal horn and unmyelinated
1) Confidence 0.45 Published 2000 Journal Brain Res. Section Abstract Doc Link 10727645 Disease Relevance 0 Pain Relevance 0.51
MDH neurons activated by stimulation of the parietal meninges were tested for convergent tactile and noxious mechanical input from all three facial branches of the trigeminal nerve.
Positive_regulation (activated) of MDH in parietal associated with fifth nerve and dorsal horn
2) Confidence 0.34 Published 1999 Journal Pain Section Abstract Doc Link 10488673 Disease Relevance 0.18 Pain Relevance 0.41

General Comments

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