INT84594

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Context Info
Confidence 0.43
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Aqp2) plasma membrane (Aqp2) protein complex (Aqp2)
transmembrane transport (Aqp2) lysosome (Aqp2) cytoplasm (Aqp2)
Anatomy Link Frequency
kidney 2
Aqp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 6 99.24 Very High Very High Very High
agonist 3 84.56 Quite High
anesthesia 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increase in free water clearance with clonidine administration was associated with a reduction in whole kidney AQP-2 mRNA levels (282+/-25 versus 216+/-11 A units, p<.05).
Negative_regulation (reduction) of Transcription (levels) of AQP-2 in kidney associated with clonidine
1) Confidence 0.43 Published 1999 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 10525117 Disease Relevance 0 Pain Relevance 0.59

General Comments

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