INT84607

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Context Info
Confidence 0.19
First Reported 1999
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Oprl1, Adrb3) signal transducer activity (Oprl1, Adrb3) aging (Adrb3)
nucleus (Adrb3)
Anatomy Link Frequency
heart 1
Oprl1 (Rattus norvegicus)
Adrb3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 7 100.00 Very High Very High Very High
MU agonist 1 80.24 Quite High
antagonist 2 53.12 Quite High
agonist 2 37.12 Quite Low
Kinase C 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Arrhythmogenic Right Ventricular Dysplasia 1 95.72 Very High Very High Very High
Coronary Artery Disease 2 94.52 High High
Arrhythmia Under Development 1 61.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since beta-adrenoceptor is negatively modulated by the kappa-opioid receptor in the heart, the present study attempted to determine if kappa-opioid receptor stimulation modulates the arrhythmogenic action of beta-adrenoceptor stimulation and to delineate the underlying mechanism.
kappa-opioid receptor Regulation (modulated) of beta-adrenoceptor in heart associated with kappa opioid receptor and arrhythmogenic right ventricular dysplasia
1) Confidence 0.19 Published 1999 Journal J. Mol. Cell. Cardiol. Section Abstract Doc Link 10525419 Disease Relevance 0.25 Pain Relevance 0.24

General Comments

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