INT84623

Context Info Confidence 0.02 First Reported 1999 Last Reported 1999 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.16 Pain Relevance 0.06

extracellular space (KAL1) extracellular region (KAL1) cell adhesion (KAL1) proteinaceous extracellular matrix (KAL1) plasma membrane (KAL1)

KAL1 (Homo sapiens)

Pain Link Frequency Relevance Heat abdominal pain 1 64.56 medulla 1 48.00

Disease Link Frequency Relevance Heat Multiple Endocrine Neoplasia Type 2a 3 88.88 Multiple Endocrine Neoplasia 1 84.60 Heart Rate Under Development 4 75.00 Pheochromocytoma 3 75.00 Dyspnea 2 74.96 Myocardial Infarction 1 72.16 Cv General 2 Under Development 1 69.76 Abdominal Pain 1 64.56 Cancer 1 53.24 Hypertension 1 50.64

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The mutation introduces a transition encoding a non-conservative substitution from TGC (Cys) to CGC (Arg) and creates a novel restriction site recognized by HhaI.

HhaI Binding (recognized) of

1) Confidence 0.02 Published 1999 Journal Tohoku J. Exp. Med. Section Abstract Doc Link 10526879 Disease Relevance 1.16 Pain Relevance 0.06

General Comments

This test has worked.