INT84637

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Context Info
Confidence 0.41
First Reported 1999
Last Reported 2002
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ntsr1) plasma membrane (Ntsr1) signal transducer activity (Ntsr1)
Anatomy Link Frequency
brain 1
Ntsr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 2 98.96 Very High Very High Very High
analgesia 4 93.44 High High
agonist 2 75.00 Quite High
Analgesic 3 72.48 Quite High
Pain 2 25.00 Low Low
Clonidine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Targeted Disruption 3 95.96 Very High Very High Very High
Hypothermia 2 51.20 Quite High
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The antihistaminic drug levocabastine is a ligand for the low affinity neurotensin receptor (NTS2).
neurotensin receptor Binding (ligand) of
1) Confidence 0.41 Published 1999 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10528128 Disease Relevance 0.05 Pain Relevance 0.48
The -/- mice lacked detectable NTR1 radioligand binding in brain, whereas NTR2 receptor binding density appeared normal compared with wild-type (+/+) mice.
NTR1 Spec (appeared) Binding (binding) of in brain
2) Confidence 0.31 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 11752130 Disease Relevance 0.10 Pain Relevance 0.04

General Comments

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