INT84731

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Context Info
Confidence 0.49
First Reported 1999
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.96
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Rtl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 92.80 High High
cytokine 6 25.00 Low Low
Inflammation 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 47 98.04 Very High Very High Very High
Alagille Syndrome 23 95.88 Very High Very High Very High
Toxicity 14 94.76 High High
Immunization 4 93.28 High High
Pain 2 92.80 High High
Skin Cancer 51 91.16 High High
Apoptosis 11 85.80 High High
Recurrence 4 75.00 Quite High
Hepatitis 1 74.96 Quite High
Breast Cancer 2 56.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
- ELISpot for gp100 and Melan A/MART-1
Positive_regulation (-) of Gene_expression (/) of MART-1
1) Confidence 0.49 Published 2008 Journal J Transl Med Section Body Doc Link PMC2265680 Disease Relevance 0.70 Pain Relevance 0
Although baseline MART-1-specific lymphoproliferative and ELISPOT responses were evident, no patient manifested increases after injection of the MART-1 plasmid.
Positive_regulation (increases) of Gene_expression (injection) of MART-1
2) Confidence 0.48 Published 2005 Journal J. Immunother. Section Abstract Doc Link 16000957 Disease Relevance 0.87 Pain Relevance 0.09
The last three patients received the MART-1(27-35) peptide with incomplete Freund's adjuvant mixed with CRL 1005, a block copolymer adjuvant.
Positive_regulation (received) of Gene_expression (received) of MART-1
3) Confidence 0.40 Published 1999 Journal Clin. Cancer Res. Section Abstract Doc Link 10537339 Disease Relevance 0.40 Pain Relevance 0

General Comments

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