INT84762

Context Info Confidence 0.22 First Reported 1999 Last Reported 1999 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.78

Golgi apparatus (B3GAT1) carbohydrate metabolic process (B3GAT1)

Anatomy Link Frequency cholinergic neurons 2 B3GAT1 (Homo sapiens)

Pain Link Frequency Relevance Heat qutenza 18 99.82 antagonist 5 80.32 Bile 3 75.00 Neurotransmitter 2 74.48 tetrodotoxin 3 46.08 Calcitonin gene-related peptide 1 25.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Tachykinins, probably released in small amounts by capsaicin, act by activating receptors of the NK1, NK2 and NK3 type, most probably located on intrinsic cholinergic neurons, which in turn release ACh to produce the final excitatory motor response.

Positive_regulation (activating) of NK1 Binding (receptors) of in cholinergic neurons associated with qutenza

1) Confidence 0.22 Published 1999 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 10543438 Disease Relevance 0 Pain Relevance 0.78

General Comments

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