INT84796

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Context Info
Confidence 0.46
First Reported 1999
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.66
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
hypothalamus 2
[[]] (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antinociception 6 100.00 Very High Very High Very High
Central grey 7 99.98 Very High Very High Very High
antagonist 2 98.98 Very High Very High Very High
withdrawal 1 90.68 High High
tail-flick 1 89.92 High High
agonist 1 83.32 Quite High
anesthesia 4 75.52 Quite High
ketamine 3 75.00 Quite High
substance P 1 73.00 Quite High
medulla 1 70.04 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 7 99.98 Very High Very High Very High
Nociception 2 71.08 Quite High
Pain 1 62.40 Quite High
Hypothermia 1 33.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies on the mediobasal hypothalamus (MBH) of rats, rhesus monkeys and goats have detected episodic increases in multiunit activity (MUA volleys) which immediately precede a pulse of luteinizing hormone (LH).
Positive_regulation (precede) of LH Binding (pulse) of in hypothalamus
1) Confidence 0.46 Published 1999 Journal Brain Res. Section Abstract Doc Link 10547003 Disease Relevance 0 Pain Relevance 0.19
In another set of experiments, the specific NK1 receptor antagonist L-703,606 (5 microg) was microinjected in the PAG following LH stimulation with carbachol abolished LH-induced antinociception as well.
Positive_regulation (following) of LH-induced Binding (antinociception) of associated with antinociception, antagonist and central grey
2) Confidence 0.44 Published 2009 Journal Neurosci. Lett. Section Abstract Doc Link 19356605 Disease Relevance 0.66 Pain Relevance 1.21

General Comments

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